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MetabolomicsPhospholipid acyl chain diversity controls the tissue-specific assembly of mitochondrial cardiolipins

Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its side chain configurations are tissue-specific, functionally important and generated via post-biosynthetic remodeling. However, this process lacks the necessary specificit...

2020-05-22 | MTBLS1446 | MetaboLights
UnknownFacile Synthesis toward the Optimal Structure-Conductivity Characteristics of the Argyrodite Li6PS5Cl Solid-State Electrolyte.
Not available
S-EPMC6172600 | biostudies-literature
ProteomicsMudPIT analyses of FLAG-DYRK1A and FLAG-Controls affinity-purified from cytoplasmic extracts of HEK293 cells
Approximately 10E9 cells for each cell line (FLAG-DYRK1A, FLAG-DYRK1A-K188R, and FLAG-controls) were collected and washed with PBS. Cells were swollen for 15 minutes in hypertonic buffer (Buffer A: 10 mM Hepes pH 7.9, 1.5 mM MgCl2, 10 mM KCl, 0.5 mM DTT) freshly supplemented with protease inhibitor ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-23 | MSV000085815 | MassIVE
MetabolomicsUntargeted Metabolomics for Integrative Taxonomy: Metabolomics, DNA Marker-Based Sequencing, and Phenotype Bioimaging

Integrative taxonomy is a fundamental part of biodiversity and combines traditional morphology with additional methods such as DNA sequencing or biochemistry. Here, we aim to establish untargeted metabolomics for use in chemotaxonomy. We used three thallose liverwort species Riccia glauca

2026-01-30 | MTBLS4668 | MetaboLights
MetabolomicsCharacterization of trotter horses urine metabolome by means of proton nuclear magnetic resonance spectroscopy
BACKGROUND: Metabolomics has been recognized as a powerful approach for disease screening. In order to highlight potential health issues in subjects, a key factor is the possibility to compare quantitatively the metabolome of their biofluids with reference values from healthy individuals. Such effor...
2019-02-12 | MTBLS675 | MetaboLights
TranscriptomicsChromatin immunoprecipitation of Streptomyces coelicolor HspR binding sites
Global ChIP-chip analysis of HspR repressor binding sites in Streptomyces coelicolor MT1110 cultures grown in YEME plus 10% sucrose at 30?C up to early stationary phase. Chromatin extracted from formaldehyde treated cultures was incubated with anti HspR polyclonal antibodies and the DNA purified f...
ORGANISM(S): Streptomyces coelicolor 
2009-02-07 | E-MAXD-48 | biostudies-arrayexpress
TranscriptomicsRheumatoid arthritis and anti-TNF treatment
In 15 patients with rheumatoid arthritis the baseline expression (t=0) of type I IFN-regulated genes was determined in peripheral blood cells (PAXgene) using cDNA-microarrays and compared to levels one month after (t=1) anti-TNF treatment (infliximab). Therefore, we used 43K cDNA microarrays from th...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-19821 | biostudies-arrayexpress
TranscriptomicsTEF-seq/NET-seq applied to factors Rpb3, Paf1, Spt6, Spt16, Cet1, Pcf11, Ssu72, Set2
Here we adapt native elongating transcript sequencing (NET-seq) to develop transcription elongation factor associated nascent elongating transcript sequencing (TEF-seq). In this the RNA polymerase II (Pol2) transcription elongation complex (TEC) is immunoprecipitated via associated transcription elo...
ORGANISM(S): Saccharomyces cerevisiae 
2021-01-18 | E-MTAB-4568 | biostudies-arrayexpress
UnknownLabelling primary immune cells using bright blue fluorescent nanoparticles.
Not available
S-EPMC7863618 | biostudies-literature
MetabolomicsStable Isotope–Assisted Plant Metabolomics: Combination of Global and Tracer-Based Labeling for Enhanced Untargeted Profiling and Compound Annotation
Untargeted approaches and thus biological interpretation of metabolomics results are still hampered by the reliable assignment of the global metabolome as well as classification and (putative) identification of metabolites. In this work we present an liquid chromatography-mass spectrometry (LC-MS)-b...
2020-02-09 | MTBLS1217 | MetaboLights
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