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UnknownGeosmin, a Food- and Water-Deteriorating Sesquiterpenoid and Ambivalent Semiochemical, Activates Evolutionary Conserved Receptor OR11A1.
Not available
S-EPMC11261619 | biostudies-literature
TranscriptomicsTenascin-C Protects Cancer Stem-Like Cells from Immune Surveillance
Precociously disseminated cancer cells may seed quiescent sites of future metastasis if they can protect themselves from immune surveillance. However, there is little knowledge about how such sites might be achieved. Here we present evidence that prostate cancer stem-like cells (CSC) can be found in...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-65502 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Methanosarcina mazei Goe1 in response to bismuth nitrate.
Pattern of gene expression of M. mazei in response to 10 uM bismuth nitrate was analyzed relative to gene expression pattern of M. mazei grown in the presence of 30 uM potassium nitrate (control cultures). Therefore, five pre-cultures of M. mazei was grown to mid-exponential growth-phase. Then, the ...
ORGANISM(S): Methanosarcina mazei 
2011-10-01 | E-MTAB-787 | biostudies-arrayexpress
GenomicsChIPseq Smad3-JMJD3
ChIP seq of endogenous Smad3 and JMJD3 proteins in mouse embryonic neural stem cells treated with TGFbeta during 30 minutes. Neural stem cells were treated with TGFbeta during 30 minutes, and then chromatin immunoprecipitation was carried out with specific JMJD3 or Smad3 antibodies. Positive and neg...
ORGANISM(S): Mus musculus 
2011-12-30 | E-MTAB-825 | biostudies-arrayexpress
TranscriptomicsEffect of 12 hour sleep restriction on the transcriptome of mice carying a human Per3 polymorphism
In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...
ORGANISM(S): Mus musculus 
2014-03-11 | E-GEOD-55494 | biostudies-arrayexpress
TranscriptomicsEffect of ultradian light-dark cycles on the transcriptome of mice carying a human Per3 polymorphism
In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...
ORGANISM(S): Mus musculus 
2014-03-11 | E-GEOD-55495 | biostudies-arrayexpress
UnknownSystematic Generation of Patient-Derived Tumor Models in Pancreatic Cancer.
Not available
S-EPMC6406729 | biostudies-literature
TranscriptomicsHuman ependymomas.
Whole-genome screening of DNA-copy number changes by array-based or matrix comparative genomic hybridization (matrix-CGH). Tumor DNA (Cy3) was hybridized against a single standard reference DNA-pool (Cy5) of the opposite sex than the patient.
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-3435 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of withdrawal of miR-155 hyperexpression in miR-155-addicted tumors
Overexpression of miR-155 in hematological tissue leads to the onset of lymphoma, and Tet-off shutdown of this overexpression reverses the disease phenotype in mir-155LSLtTA mice. This study compares the gene expression profiles of tumors with miR-155 overexpression and withdrawal. Examination of mR...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-61851 | biostudies-arrayexpress
TranscriptomicsDirect Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
Recent advances in the stem cell biology have revealed that cell type-specific transcription factors could reset the somatic memory and induce direct reprogramming into specific cellular identities. The induction of pluripotency in terminally differentiated cells has been a major achievement in the ...
ORGANISM(S): Mus musculus 
2012-05-02 | E-GEOD-30500 | biostudies-arrayexpress
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