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While the majority of RNA polymerase II initiation events in mammalian genomes take place within CpG island (CGI) promoters, our understanding of their regulation remains limited. Here we combine single-molecule footprinting with interaction proteomics to identify BANP as a critical CGI regulator an...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-16 | PXD024794 | Pride
BANP opens chromatin and activates CpG island regulated genes [ChIP-Seq]
BANP opens chromatin and activates CpG island regulated genes [ATAC-Seq]
BANP opens chromatin and activates CpG island regulated genes [MNase-seq]
BANP opens chromatin and activates CpG island regulated genes [SLAM-Seq]
BANP opens chromatin and activates CpG island regulated genes [RNA-Seq]
In mammalian genomes, the vast majority of RNA polymerase II initiation events take place at CpG island promoters. Despite their relevance our understanding of their regulation remains limited. Here we identify Banp as the long sought-after TF that binds the orphan CGCG element in CpG islands by com...
ORGANISM(S): Mus musculus 
2021-05-17 | GSE155600 | GEO
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