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TranscriptomicsMicroRNA profiling of adult male zebrafish exposed to 17-beta estradiol (E2) for 0, 1, 4. 12 and 24 hours
Microarrays displaying zebrafish miRNAs specific probes were hybridized using RNA samples originating from whole body homogenates of male zebrafish exposed to 17-beta estradiol (E2) for 0, 1, 4. 12 and 24 hours. 0 hr fish No. 40, 41, 42. 1hr fish No. 8, 10, 11. 4hr fish No. 19, 20, 23. 12hr fish N...
ORGANISM(S): Danio rerio 
2007-12-30 | E-MEXP-1147 | biostudies-arrayexpress
UnknownGlobal perspectives on the contribution of B cells to multiple sclerosis: an in-depth examination and evaluation.
Not available
S-EPMC11602428 | biostudies-literature
TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of liver from vitellogenic and non-vitellogenic zebrafish females
Liver samples were collected from zebrafish females (3 months old). Vitellogenic females were maintained under conditions of 14 h light: 10 h dark. Non-vitellogenic females were obtained by exposing females to 6 h light/18 h dark regime.
ORGANISM(S): Danio rerio 
2009-10-01 | E-MEXP-1572 | biostudies-arrayexpress
TranscriptomicsDifferential regulation of SGK1 by progesterone activates AP-1/NDRG1 genomic axis in PR-positive and negative breast cancer cells
Pre-operative progesterone intervention has been shown to confer a survival benefit to breast cancer patients independent of their progesterone receptor (PR) status, raising a question about how progesterone affects the outcome of PR-negative cells. Here, we identify up-regulation of a Serum- and gl...
ORGANISM(S): Homo sapiens 
2018-10-19 | E-MTAB-6742 | biostudies-arrayexpress
TranscriptomicsTime course experiment of 17β-estradiol (E2) treatment in the zebrafish
Transcriptional profiling of zebrafish (Danio rerio) livers comparing control untreated fish with fish treated with estrogen [17β-estradiol (E2)] for different time points (4, 12, 24, 48 hours). For the assay experimental design, RNA from one of three different E2-treated fish (representing three b...
ORGANISM(S): Danio rerio 
2013-06-28 | E-GEOD-45562 | biostudies-arrayexpress
TranscriptomicsEstrogen regulation of microRNA in the zebrafish liver
Microarrays displaying zebrafish microRNA specific probes were hybridized using RNA samples originating from livers of male zebrafish exposed to 17-beta estradiol (E2) for 0, 24 and 48 hours.
ORGANISM(S): Danio rerio 
2013-06-02 | E-MEXP-3866 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile in HOS cells exposed to sodium fluoride
Fluorosis is caused due to excess of fluoride intake over a long period of time. Aberrant change in RUNX2-mediated signaling cascade is one of the decisive steps during the pathogenesis of fluorosis. Till date, role of fluoride on the epigenetic alterations is not studied. In the present study, glob...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-57550 | biostudies-arrayexpress
TranscriptomicsColony stimulating factor-1 receptor signaling networks inhibit macrophage inflammatory responses by induction of microRNA-21
Macrophage polarization between the M2 (repair, pro-tumorigenic) and M1 (inflammatory) phenotypes is seen as a continuum of states. The detailed transcriptional events and signals downstream of CSF-1R that contribute to amplification of the M2 phenotype and suppression of the M1 phenotype are largel...
ORGANISM(S): Mus musculus 
2014-10-23 | E-GEOD-62630 | biostudies-arrayexpress
TranscriptomicsArgonaute2 mediates compensatory expansion of the pancreatic M-CM-^_-cell
Pancreatic M-CM-^_-cells adapt to compensate for the increased metabolic demand during insulin resistance. While the microRNA pathway has an essential role in the expansion of M-CM-^_-cell mass, the extent of its contribution is unclear. Here we show that miR-184 is silenced in the pancreatic islets...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-46623 | biostudies-arrayexpress
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