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Unknown#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol.
Not available
S-EPMC8609898 | biostudies-literature
TranscriptomicsTranscription profiling of mouse intestinal cells expressing Lgr5 at high or low levels or with Ascl2 conditionally knocked out shows Ascl2 controls intestinal stem cell fate
The small intestinal epithelium is the most rapidly self-renewing tissue of mammals. Proliferative cells are confined to crypts, while differentiated cell types predominantly occupy the villi. We recently demonstrated the existence of a long-lived pool of cycling stem cells defined by Lgr5 expressio...
ORGANISM(S): Mus musculus 
2009-03-25 | E-GEOD-14201 | biostudies-arrayexpress
TranscriptomicsCombined MYC and TP53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease [gene expression]
We undertook a comprehensive clinical and biological investigation of serial medulloblastoma biopsies obtained at diagnosis and relapse. Combined MYC gene family amplifications and P53 pathway defects commonly emerged at relapse, and all patients in this molecular group died of rapidly progressive d...
ORGANISM(S): Mus musculus 
2015-04-23 | E-GEOD-62625 | biostudies-arrayexpress
TranscriptomicsExpression profiling following SMARCB1 re-expression in MRT cell lines time course over 14 days
MRT cell lines KD, SWOH, LM, DEV and G401 were expression profiled following SMARCB1 re-expression using a lentivirus. Samples were taken at Day 0,1,3,7 and 14 and compared to empty vector control experiments.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-6674 | biostudies-arrayexpress
TranscriptomicsPaneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
Homeostasis of self-renewing small intestinal crypts results from neutral competition between Lgr5 stem cells, small cycling cells located at crypt bottoms1, 2. Lgr5 stem cells are interspersed between terminally differentiated Paneth cells, that are known to produce bactericidal products such as ly...
ORGANISM(S): Mus musculus 
2010-11-29 | E-GEOD-25109 | biostudies-arrayexpress
TranscriptomicsRole of a Candida albicans Whi5/Nrm1 homolog in cell cycle and hyphal-specific gene expression
Candida albicans is an opportunistic pathogenic fungus that is able to assume several morphologies, including yeast and hyphal growth forms. The hyphal morphology can be induced by various environmental stimuli and is accompanied by expression of a large set of hyphal-specific genes (HSGs). Cell cyc...
ORGANISM(S): Candida albicans 
2012-01-01 | E-GEOD-20612 | biostudies-arrayexpress
UnknownDraft Whole-Genome Sequence of Penicillium simplicissimum A4, a Putative Endophyte from Echium plantagineum.
Not available
S-EPMC9671005 | biostudies-literature
TranscriptomicsSingle intestinal stem cells build crypt-villus structures in vitro without a cellular niche
The intestinal epithelium is the most rapidly self-renewing tissue in adult mammals. We have recently demonstrated the presence of approximately six cycling Lgr5+ stem cells at the bottoms of small intestinal crypts1. We have now established long-term culture conditions under which single crypts und...
ORGANISM(S): Mus musculus 
2009-04-03 | E-GEOD-14594 | biostudies-arrayexpress
TranscriptomicsCOMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS
This SuperSeries is composed of the following subset Series: GSE23672: COMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AGILENT ARRAYS) GSE33948: COMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AFFYMETRIX ARRAYS...
ORGANISM(S): Mus musculus 
2012-08-12 | E-GEOD-33949 | biostudies-arrayexpress
UnknownDiscovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design.
Not available
S-EPMC4834655 | biostudies-literature
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