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TranscriptomicsTranscription profiling of human samples of multiple myeloma patients with and without bone lytic lesion by MRI
This series represents samples of multiple myeloma patients with and without bone lytic lesion by MRI.
ORGANISM(S): Homo sapiens 
2007-09-25 | E-GEOD-755 | biostudies-arrayexpress
UnknownMinimal residual disease negativity by next-generation flow cytometry is associated with improved organ response in AL amyloidosis.
Not available
S-EPMC7887224 | biostudies-literature
TranscriptomicsPredict cytogenetic abnormalities with gene expression profiles
Cytogenetic abnormalities (CA) are important clinical parameters in various types of cancer, including multiple myeloma (MM). We developed a model to predict CA in patients with MM using gene expression profiling (GEP) and validated it by different cytogenetic techniques. The model was shown to have...
ORGANISM(S): Homo sapiens 
2012-06-11 | E-GEOD-29023 | biostudies-arrayexpress
GenomicsGenomic alterations in MM - CEL
RNA from the same tumor sample (n=98) was also processed using the 3' IVT kit (Affymetrix) and hybridized to U133 Plus 2.0 arrays (Affymetrix).
EGAD00010001577 | EGA
Genomicsena-DATASET-UAMS-11-05-2018-20:15:20:859-1971 - samples
Tumor DNA was extracted from 100 bone marrow aspirate samples where CD138+ selection had been performed to enrich plasma cells from patients with multiple myeloma. Patient matched control DNA from either peripheral blood leukocytes or CD34+ stem cell harvests was also isolated. Both tumor and contro...
EGAD00001004117 | EGA
TranscriptomicsPlasma cells from 52 patients with multiple myeloma: mRNA and miRNA expression profiling
We used microarray analyses of patient myeloma cells (n=52) to correlate individual miRNA expression profiles with GEP-based risk defined by mRNA expression profilesx as well as clinical features of the disease. Unlike for mRNAs, genome-wide elevation of miRNA expression patterns were significantly ...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-17306 | biostudies-arrayexpress
GenomicsTargeted panel data for newly diagnosed myeloma patients.
Genomic abnormalities in MM are common and can affect a patients outcome. Here we have performed targeted sequencing on xx patient tumor samples and matched control DNA. The targeted panel consists of ~160 genes and copy number regions, as well as key regions of chromosomal translocation including ...
EGAS00001002859 | EGA
TranscriptomicsGene expression of expanded and non-expanded natural killer cells from healthy donor and myeloma patients
Natural Killer cells (NK), a major constituent of innate immune system, have the ability to kill the transformed and infected cells without prior sensitization; can be put to immunotherapeutic use against various malignancies. NK cells discriminate between normal cells and transformed cells via a ba...
ORGANISM(S): Homo sapiens 
2011-03-08 | E-GEOD-27838 | biostudies-arrayexpress
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