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UnknownCirculating neutrophils levels are a predictor of pneumonia risk in chronic obstructive pulmonary disease.
Not available
S-EPMC6708190 | biostudies-literature
TranscriptomicsGene Expression Data of Hibernating and Summer Active Black Bears
We conducted a large-scale gene expression screen using the 3,200 cDNA probe microarray developed specifically for Ursus americanus to detect expression differences in liver and skeletal muscle that occur during winter hibernation in comparison to animals sampled during summer. The expression of 12 ...
ORGANISM(S): Ursus americanus 
2009-03-09 | E-GEOD-15099 | biostudies-arrayexpress
TranscriptomicsModulation of gene expression in heart and liver of hibernating black bears (Ursus americanus)
We analyzed gene expression in the American black bear, Ursus americanus, using a custom 12,800 cDNA probe (BA02) microarray to detect differences in expression that occur in heart and liver during winter hibernation in comparison to summer active animals. We identified 245 genes in heart and 319 ge...
ORGANISM(S): Ursus americanus 
2011-05-10 | E-GEOD-27875 | biostudies-arrayexpress
TranscriptomicsImmune cells direct epithelial maturation during early human lung development
The adult human lung harbours a significant proportion of immune cells, which are known to play a crucial role in both normal lung homeostasis and pathogenesis. In this work, we collected CD45-enriched human lung cells from 6 to 22 week post conception (pcw) and built a single-cell transcriptome and...
ORGANISM(S): Homo sapiens 
2022-12-09 | E-MTAB-11528 | biostudies-arrayexpress
TranscriptomicsAnalysis of molecular signatures in mammalian hibernation
Mammalian hibernators display phenotypes similar to physiological conditions in non-hibernating species under conditions of calorie restriction and fasting, hypoxia, hypothermia, ischemia-reperfusion, and sleep. However, whether or how similarities are also reflected on molecular and genetic levels ...
ORGANISM(S): Urocitellus parryii 
2012-09-01 | E-GEOD-38700 | biostudies-arrayexpress
UnknownPrediction of respiratory decompensation in Covid-19 patients using machine learning: The READY trial.
Not available
S-EPMC7410013 | biostudies-literature
UnknownCrisis resolution and home treatment: stakeholders' views on critical ingredients and implementation in England.
Not available
S-EPMC5512942 | biostudies-literature
TranscriptomicsExpression data for human epithelium from subjects with atopic dermatitis, psoriasis and nonatopic controls
The expression and function of tight junction genes, in particular claudin-1, was studied in order to further understanding of the biology underlying atopic dermatitis. Gene expression profiling was performed on total RNA from nonlesional epidermal samples from 5 subjects with atopic dermatitis, 4 s...
ORGANISM(S): Homo sapiens 
2011-01-29 | E-GEOD-26952 | biostudies-arrayexpress
ModelsShankaran2018 - Systems Pharmacology Model of Gastrointestinal Damage
Model predicted time course of enterocyte loss in patients treated with weekly doses matched observed AE profiles. The model also correctly predicts a lower level of AEs for every 3 weeks (Q3W), as compared to the weekly schedule.
2021-10-26 | MODEL2110260001 | BioModels
TransQST 
TranscriptomicsPreservation of bone mass and structure in hibernating black bears (Ursus americanus) through elevated expression of anabolic genes
Physical inactivity reduces mechanical load on the skeleton, which leads to losses of bone mass and strength in non hibernating mammalian species. Although bears are largely inactive during hibernation, they show no loss in bone mass and strength. To obtain insight into molecular mechanisms preventi...
ORGANISM(S): Ursus americanus 
2012-02-15 | E-GEOD-35796 | biostudies-arrayexpress
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