Sort   by:  
 Page size 
TranscriptomicsRole of FliL in Swarmer Cell Differentiation
Proteus mirabilis is an opportunistic pathogen that causes urinary tract infections in immunocompromised patients. Flagellar motility coupled with the ability to differentiate from short swimmer cells to highly elongated swarmer cells constitute key parts of the infection process. The mechanism by w...
ORGANISM(S): Proteus mirabilis 
2011-11-15 | E-GEOD-30810 | biostudies-arrayexpress
ProteomicsMice with FIA develop anti-native and anti-in vitro citrullinated fibrinogen antibodies
Synovial antigen arrays were probed with 1:150 dilutions of plasma derived from SJL mice immunized with fibrinogen emulsified in CFA or with CFA alone. Autoantibody binding was detected with a Cy3-conjugated goat-anti-mouse IgG/M secondary antibody. SAM was applied to identify antigens with statis...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18023 | biostudies-arrayexpress
ProteomicsFIA plasma induces arthritis in naïve mice
Plasma collected from mice with FIA were pooled, and 0.3 ml was injected intravenously into 6-week-old naïve SJL mice on days 0 and 2. Synovial antigen array profiling of plasma from the arthritic recipient mice demonstrated autoreactive B-cell responses against peptides representing native fibrino...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18024 | biostudies-arrayexpress
ProteomicsFibrinogen-reactive T cells transfer disease to naïve mice
Splenocytes harvested from mice with FIA were cultured in vitro and stimulated with 0.01 mg/ml fibrinogen for 3 days. Enriched T cells were transferred into 6-week-old naïve SJL mice, which developed visible signs of arthritis within 2 weeks. Synovial array profiling of plasma from the arthritic ...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18025 | biostudies-arrayexpress
TranscriptomicsWhole transcriptome analysis of FACS purified somatosensory neuron subtypes and whole dorsal root ganglia tissue
The goal of this study was to analyze global gene expression in specific populations of somatosensory neurons in the periphery, including major, non-overlapping populations that include nociceptors, pruriceptors, and prorioceptors. The mammalian somatosensory nervous system encodes the perception of...
ORGANISM(S): Mus musculus 
2014-12-23 | E-GEOD-55114 | biostudies-arrayexpress
UnknownCOVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study.
Not available
S-EPMC9240087 | biostudies-literature
UnknownChanges in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study.
Not available
S-EPMC8041365 | biostudies-literature
UnknownRecurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.
Not available
S-EPMC8185188 | biostudies-literature
TranscriptomicsRobust axonal regeneration occurs in the injured CAST/Ei mouse central nervous system
Axon regeneration in the central nervous system (CNS) requires reactivating injured neurons’ intrinsic growth state and enabling growth in an inhibitory environment. Using an inbred mouse neuronal phenotypic screen, we find that CAST/Ei mouse adult dorsal root ganglion neurons extend axons more on C...
ORGANISM(S): Mus musculus 
2015-07-22 | E-GEOD-67130 | biostudies-arrayexpress
UnknownMutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of α-dystroglycan.
Not available
S-EPMC3710768 | biostudies-literature
Sort   by:  
 Page size