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TranscriptomicsSystems analysis of uterine microenvironment in Treg depleted pregnant mice at 12 days after fertilization
Analysis of uterine microenvironment at gene expression level. The hypothesis tested in the present study was that Tregs orchestrated the immune reponse triggered in presence of embryo. Total RNA obtained from uterine microenvironment tissues of Treg depleted pregnant mice (12 days after fertilizati...
ORGANISM(S): Mus musculus 
2015-12-10 | E-GEOD-68432 | biostudies-arrayexpress
TranscriptomicsRNA-seq of two hybrid mouse embryonic stem cell lines in a competitive environment during pluripotency: comparison between separate and co-culture conditions
Compared two hybrid mouse embryonic stem cell lines (that contain the same nuclear background, but different mtDNA content) in separate and co-culture conditions. We investigated the genes differentially expressed between these two cell lines in separate and co-culture as well as the genes that chan...
ORGANISM(S): Mus musculus 
2020-01-18 | E-MTAB-8692 | biostudies-arrayexpress
TranscriptomicsHuman iPSC-derived cardiomyocytes of peripartum cardiomyopathy patients reveal aberrant expression of sterol and lipid metabolism pathways
To identify the consequences of mechanical stress of differentiated cardiac muscles from healthy- and PPCM individuals. RNA-sequencing data was obtained from 4 individuals from 2 families. Each family had one member with PPCM and one healthy. Individual 1 and 2 were sisters, one healthy, one with PP...
ORGANISM(S): Homo sapiens 
2020-12-08 | E-MTAB-9053 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA sequencing of CellTagging lung organoids
Here, we used a lentiviral-based barcoding method (CellTagging) to lineage trace progenitor cells in a human lung organoid model. 21-day cultures were transduced for 7 days, fluorescence activated cell sorted for GFP+ expression, and regrown as sparsely plated cells for additional 30 days before seq...
ORGANISM(S): Homo sapiens 
2023-04-21 | E-MTAB-12753 | biostudies-arrayexpress
TranscriptomicsFra1 silencing in MDA-MB-231 cells
Fra1 silencing in MDA-MB-231 cells
ORGANISM(S): Homo sapiens 
2013-07-24 | E-MTAB-1230 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of human fetal lung explants with R-SPONDIN Inhibition and human fetal lung primary tissue
Here, we used single cell RNA-sequencing (scRNA-seq) to profile 13-week post-conception distal human fetal lung explants cultured in an air liquid interface system and treated with an LGR5 ectodomain adenovirus that inhibits R-Spondin function or control adenovirus. A third, non-infected, condition ...
ORGANISM(S): Homo sapiens 
2022-01-01 | E-MTAB-10662 | biostudies-arrayexpress
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