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TranscriptomicsTranscription profiling of human atrial and ventricular myocardium from patients atrial tissue of patients with sinus rhythm vs. human left ventricular non-failing myocardium to identify the transcriptional basis for ultrastructural and functional specialization of human atria and ventricles
Note this data set has identical data files: Files GSM40994.txt and GSM40995.txt. GSE2240 contains two different experimental subsets:; 1) Comparison of atrial and ventricular gene expression (atrial tissue of patients with sinus rhythm vs. human left ventricular non-failing myocardium); The purpose...
ORGANISM(S): Homo sapiens 
2007-10-27 | E-GEOD-2240 | biostudies-arrayexpress
TranscriptomicsGenome-wide changes in gene expression during the development and after recovery from heart failure in a mouse model of transient cardiomyopathy.
Altered myocardial gene expression from heart failure (HF) has mostly been identified by single-point analysis of end-stage disease. This may miss earlier changes in gene expression that are transient and/or directionally opposite to those observed later. By sampling left ventricular myocardial tis...
ORGANISM(S): Mus musculus 
2014-11-03 | E-GEOD-54681 | biostudies-arrayexpress
UnknownPrimary limited lumbar discectomy with an annulus closure device: one-year clinical and radiographic results from a prospective, multi-center study.
Not available
S-EPMC4430560 | biostudies-literature
TranscriptomicsCardiac Resynchronization Therapy Corrects Dyssynchrony-induced Regional Gene Expression Changes on a Genomic Level
This SuperSeries is composed of the following subset Series: GSE14327: Cardiac Resynchronization Therapy (1-color design) GSE14338: Cardiac Resynchronization Therapy (2-color design) Refer to individual Series
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14661 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human heart with heart failure due to ischemic cardiomyopathy or dilated cardiomyopathy
End stage heart failure due to ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) have similar characteristics, enlargement of the ventricles, relatively thin-walled ventricle, which leads to a limited contraction force and blood loading. Nevertheless, the response for present therapeuti...
ORGANISM(S): Homo sapiens 
2007-10-31 | E-CVDE-1 | biostudies-arrayexpress
TranscriptomicsCardiac Resynchronization Therapy (2-color design)
Objectives: To test whether (1) electromechanical dyssynchrony induces region-specific alterations in the myocardial transcriptome and (2) dyssynchrony-induced gene expression changes can be corrected by cardiac resynchronization (CRT). Background: To date, CRT is the only heart failure treatment th...
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14338 | biostudies-arrayexpress
TranscriptomicsCardiac Resynchronization Therapy (1-color design)
Objectives: To test whether (1) electromechanical dyssynchrony induces region-specific alterations in the myocardial transcriptome and (2) dyssynchrony-induced gene expression changes can be corrected by cardiac resynchronization (CRT). Background: To date, CRT is the only heart failure treatment th...
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14327 | biostudies-arrayexpress
ProteomicsIdentification of Drosophila centromere associated proteins
affinity purification-MS analysis of Drosophila centromeric chromatin
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2014-07-31 | PXD000758 | Pride
Drosophila melanogaster Lc-ms/ms 
ProteomicsTwo distinct modes for propagation of histone PTMs across the cell cycle
Epigenetic states defined by chromatin can be maintained through mitotic cell division. However, it remains unknown how histone-based information is transmitted. Here we combine nascent chromatin capture (NCC) and triple-SILAC labelling to track histone modifications and histone variants during DNA ...
ORGANISM(S): Homo sapiens (Human) 
2015-03-30 | PXD001980 | Pride
Ncc  histone modifications  inheritance  chromatin  epigenetics 
TranscriptomicsTranscription profiling of human Burkitts lymphomas
The distinction between the Burkitt lymphoma and diffuse large B-cell lymphoma is imprecise using current diagnostic criteria. We applied transcriptional and genomic profiling to molecularly define Burkitt lymphoma. Gene expression profiling employing Affymetrix GeneChips (U133A) was performed in 22...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4475 | biostudies-arrayexpress
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