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Dynamic recycling and de novo deposition of histones are fundamental for chromatin restoration. Histone post-translational modifications (PTMs) are assumed to have a causal role in establishing distinct chromatin structures. However, it remains unknown how specific histone PTMs are regulated at brok...
ORGANISM(S): Homo sapiens (Human) 
2021-01-18 | PXD018220 | Pride
Kregervanrija delftensis strain:NCC-J Genome sequencing and assembly
Bifidobacterium longum strain:NCC 5000 2951181949(IMG) Genome sequencing
The thiazide-sensitive NaCl cotransporter (NCC) is an important pharmacological target in the treatment of hypertension. Human SLC12A3 gene encoding NCC gives rise to three isoforms. Only the isoform 3 has been extensively investigated. The goal of the present study was, therefore, to determine the ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080722 | MassIVE
Human isolate that has immunomodulation properties and inhibits pathogens
Transcriptome analysis of iTeO, TeO and NCC
Combining an in vitro hNCC differentiation protocol with epigenomic profiling, we provide the first whole-genome characterization of cis-regulatory elements in this highly relevant cell type. With this data at hand, we have characterized the chromatin state and dynamics of all human gene promoters d...
ORGANISM(S): Gallus gallus 
Draft genome sequence of Mycolicibacterium sp. strain Tsukiji isolated from blood culture of hematooncology patient.
Chromatin organization must be maintained during cell proliferation to preserve cellular identity and genome integrity. However, DNA replication results in transient displacement of DNA bound proteins, and it is unclear how they regain access to newly replicated DNA. Using quantitative MS-based prot...
ORGANISM(S): Homo sapiens (Human) 
2023-02-02 | PXD035489 | Pride
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