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TranscriptomicsTranscription profiling of human atrial and ventricular myocardium from patients atrial tissue of patients with sinus rhythm vs. human left ventricular non-failing myocardium to identify the transcriptional basis for ultrastructural and functional specialization of human atria and ventricles
Note this data set has identical data files: Files GSM40994.txt and GSM40995.txt. GSE2240 contains two different experimental subsets:; 1) Comparison of atrial and ventricular gene expression (atrial tissue of patients with sinus rhythm vs. human left ventricular non-failing myocardium); The purpose...
ORGANISM(S): Homo sapiens 
2007-10-27 | E-GEOD-2240 | biostudies-arrayexpress
TranscriptomicsCardiac Resynchronization Therapy Corrects Dyssynchrony-induced Regional Gene Expression Changes on a Genomic Level
This SuperSeries is composed of the following subset Series: GSE14327: Cardiac Resynchronization Therapy (1-color design) GSE14338: Cardiac Resynchronization Therapy (2-color design) Refer to individual Series
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14661 | biostudies-arrayexpress
TranscriptomicsCardiac Resynchronization Therapy (2-color design)
Objectives: To test whether (1) electromechanical dyssynchrony induces region-specific alterations in the myocardial transcriptome and (2) dyssynchrony-induced gene expression changes can be corrected by cardiac resynchronization (CRT). Background: To date, CRT is the only heart failure treatment th...
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14338 | biostudies-arrayexpress
TranscriptomicsCardiac Resynchronization Therapy (1-color design)
Objectives: To test whether (1) electromechanical dyssynchrony induces region-specific alterations in the myocardial transcriptome and (2) dyssynchrony-induced gene expression changes can be corrected by cardiac resynchronization (CRT). Background: To date, CRT is the only heart failure treatment th...
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14327 | biostudies-arrayexpress
ProteomicsTwo distinct modes for propagation of histone PTMs across the cell cycle
Epigenetic states defined by chromatin can be maintained through mitotic cell division. However, it remains unknown how histone-based information is transmitted. Here we combine nascent chromatin capture (NCC) and triple-SILAC labelling to track histone modifications and histone variants during DNA ...
ORGANISM(S): Homo sapiens (Human) 
2015-03-30 | PXD001980 | Pride
Ncc  histone modifications  inheritance  chromatin  epigenetics 
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