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ProteomicsEvaluation of NHS-Acetate and DEPC labelling for determination of solvent accessible amino acid residues in protein complexes
The structural analysis of proteins and protein complexes is key for understanding their function and regulation. In order to gain structural information, we examined protein surface labelling using NHS-Acetate and DEPC following an MS-based workflow. Using two model proteins we characterise the obt...
ORGANISM(S): Oryctolagus cuniculus cuniculus Saccharomyces cerevisiae (Baker's yeast) 
2020-05-05 | PXD015940 | Pride
Diethylpyrocarbonate N-hydroxysuccinimidyl acetate Mass spectrometry Neutral loss Chemical labelling Solvent accessible surface area Labelling percentage 
UnknownChemical Modulation of in Vivo Macrophage Function with Subpopulation-Specific Fluorescent Prodrug Conjugates.
Not available
S-EPMC5620981 | biostudies-literature
UnknownSaturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4.
Not available
S-EPMC6697720 | biostudies-literature
ProteomicsViral immune evasions differentially impact cell surface presentation of MHC I allomorphs already at the peptide-loading complex
The transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the endoplasmic reticulum (ER) where they are loaded onto major histocompatibility class I (MHC I) molecules. Stable peptide-MHC I complexes travel to the cell surface and present their antigenic car...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027408 | Pride
Er quality control Major histocompatibility complex class i Mass spectrometry Mhc i biogenesis Viral immune evasion Peptide-loading complex 
UnknownImproved overall survival of metastatic renal cell carcinoma patients in the era of modern tyrosine kinase inhibitors and immune checkpoint inhibitors: results from a real-life, population-based Austrian study comprising three decades of follow-up.
Not available
S-EPMC9679616 | biostudies-literature
UnknownEnzyme-Activatable Chemokine Conjugates for In Vivo Targeting of Tumor-Associated Macrophages.
Not available
S-EPMC9826351 | biostudies-literature
UnknownEnzyme-Activatable Chemokine Conjugates for In Vivo Targeting of Tumor-Associated Macrophages.
Not available
S-EPMC10946784 | biostudies-literature
UnknownFish larval recruitment to reefs is a thyroid hormone-mediated metamorphosis sensitive to the pesticide chlorpyrifos.
Not available
S-EPMC5662287 | biostudies-literature
ProteomicsCross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes
Synaptic vesicles are storage organelles for neurotransmitters in the pre-synaptic cytosol. When an action potential arrives at the pre-synaptic terminal, they fuse with the pre-synaptic membrane and neurotransmitters are released. In this project, we set out to study the protein interactions formed...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-12-09 | PXD020859 | Pride
Chemical cross-linking Mass spectrometry Protein networks Synaptic vesicles Synaptophysin Synaptobrevin-2 
UnknownImproved susceptibility weighted imaging at ultra-high field using bipolar multi-echo acquisition and optimized image processing: CLEAR-SWI.
Not available
S-EPMC7612087 | biostudies-literature
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