Sort   by:  
 Page size 
GenomicsChIP-seq mapping of histone modifications in CD14++ CD16- monocytes from human blood samples
Chromatin immunoprecipitation in combination with a genome-wide analysis via high-throughput sequencing is the state of the art method to gain genome-wide representation of histone modification or transcription factor binding profiles. However, chromatin immunoprecipitation analysis in the context o...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-54634 | biostudies-arrayexpress
GenomicsDifferential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and exon sequences
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-02-08 | E-GEOD-41010 | biostudies-arrayexpress
GenomicsCTCF/CP190 and ISWI dependent regulation of nucleosome occupancy [ChIP-seq]
H3-ChIP-seq was performed in order to analyze changes in nucleosomal occupancy after depletion of CTCF/P190 and ISWI from Drosophila S2 cells Histone H3 ChIP-seq from Drosophila S2 cells after CTCF/CP190 or ISWI-specific RNAi treatment
ORGANISM(S): Drosophila melanogaster 
2014-08-11 | E-GEOD-51598 | biostudies-arrayexpress
GenomicsCTCF/CP190 and ISWI dependent regulation of nucleosome occupancy [MNase-seq]
MNase-seq was performed in order to analyze changes in nucleosomal occupancy after depletion of CTCF/P190 and ISWI from Drosophila S2 cells MNase-seq from Drosophila S2 nuclei after CTCF/CP190 or ISWI-specific RNAi treatment
ORGANISM(S): Drosophila melanogaster 
2014-08-11 | E-GEOD-51599 | biostudies-arrayexpress
TranscriptomicsAnalysis of genome-wide binding of the insulator factors CTCF and CP190
We identified about 3000 CTCF sites in the genome. In addition to binding to CTCF sites we found CP190 to bind to transcriptional start sites of actively transcribed genes where it inversely correlates with nucleosome occupancy. Keywords: ChIP-chip CTCF and CP190 ChIP. 2 biological replicates per e...
ORGANISM(S): Drosophila melanogaster 
2010-05-05 | E-GEOD-12749 | biostudies-arrayexpress
GenomicsGenome-wide identification of MBD2 and MBD3 binding sites by ChIP-seq
The heterogeneous collection of NuRD complexes can be grouped into the MBD2 or MBD3 containing complexes MBD2-NuRD and MBD3-NuRD. Although functional differences have been described, a direct comparison of MBD2 and MBD3 in respect to genome-wide binding and function has been lacking. Here we show a ...
ORGANISM(S): Homo sapiens 
2013-02-08 | E-GEOD-41006 | biostudies-arrayexpress
TranscriptomicsThe activation of IL-1 induced enhancers depends on TAK1 kinase activity and NF-KB p65
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-12-16 | E-GEOD-64224 | biostudies-arrayexpress
TranscriptomicsExpression data from HeLa cells after MBD2 and MBD3 knock down
The heterogeneous collection of NuRD complexes can be grouped into the MBD2 or MBD3 containing complexes MBD2-NuRD and MBD3-NuRD. MBD2 is known to bind to methylated CpG sequences in vitro in contrast to MBD3. Although functional differences have been described, a direct comparison of MBD2 and MBD3 ...
ORGANISM(S): Homo sapiens 
2013-02-08 | E-GEOD-41003 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in wild-type Drosophila testes with tbrd-1 mutant testes
Gene expression is tightly linked to histone acetylation on lysine residues that can be recognized by bromodomains. The testis-specific bromodomain protein tBRD-1 is essential for male fertility and might act as a co-factor of testis-specifc TAFs. Here, we perform microarray analyses and demonstrate...
ORGANISM(S): Drosophila melanogaster 
2014-08-08 | E-GEOD-52511 | biostudies-arrayexpress
GenomicsChIP-seq mapping of histone modifications in CD14++ CD16- monocytes from septic disease patients
Chromatin immunoprecipitation with antibodies specific for histone modifications H3K4me3, H3K9ac and H3K27me3 and subsequent high-throughput sequencing were performed on fixed chromatin from two septic disease patients. ChIP-seq
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-62908 | biostudies-arrayexpress
Sort   by:  
 Page size