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ProteomicsProteomic profiling of ectodermal basal disc cells secretion of Hydra
Biological adhesion (bioadhesion) is referred to attachment of organisms to either biotic or abiotic surfaces. The differentiated ectodermal basal disc cells of the freshwater cnidarian Hydra secrete proteinaceous glue to temporarily attach themselves to surfaces underwater. In this study, we invest...
ORGANISM(S): Hydra vulgaris 
2017-08-18 | PXD004899 | Pride
Basal disc Bioadhesion Hydra 
Modelsstseranidou2024 - Nucleus Pulposus Cell Network Modelling in the Intervertebral Disc
ABSTRACT: Intervertebral disc degeneration (IDD) arises from an intricate imbalance between the anabolic and catabolic processes governing the extracellular matrix (ECM) within the disc. Biochemical processes are complex, redundant and feedback-looped, and improved integration of knowledge i...
2024-11-04 | MODEL2407080001 | BioModels
GenomicsThe BTB-zinc finger transcription factor Abrupt acts as an epithelial oncogene in Drosophila through maintaining a progenitor-like cell state
The capacity of tumor cells to maintain continual overgrowth potential has been linked to the commandeering of normal self-renewal pathways. Using an epithelial cancer model in Drosophila we carried out an overexpression screen for oncogenes capable of cooperating with the loss of the epithelial api...
ORGANISM(S): Drosophila melanogaster 
2013-08-15 | E-GEOD-42928 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of stalk-eyed fly lines selected for divergent eyespan
Eye-stalks of some flies exhibit extreme sexual dimorphism, but little is known about the genetic mechanisms producing variation in these ornamental traits. Therefore, we constructed an EST database of genes expressed in the developing eye-antennal imaginal disc of the highly dimorphic species, Tele...
ORGANISM(S): Teleopsis dalmanni 
2010-06-24 | E-GEOD-15444 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Su(H) induced wing disc hyperplasia
The outcome of Notch activation of proliferation depends on cellular context. In Drosophila wing discs Notch pathway overactivation results in hyperplasia. To understand the mechanisms we have used genomic strategies to indetify the Notch-S(H) target genes directly regulated in wing disc hyperplasia...
ORGANISM(S): Drosophila melanogaster 
2013-12-31 | E-GEOD-41427 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Gerbera-Ray vs Disc flowers
Three different developmental stages of ray and disc flowers of gerbera hybrida were compared to each other using gerbera 9K cDNA microarray.
ORGANISM(S): Gerbera hybrid cultivar 
2005-12-31 | E-MEXP-418 | biostudies-arrayexpress
TranscriptomicsGene expression changes in Nicd induced wing disc hyperplasia
The outcome of Notch proliferation on proliferation depends on the context. In Drosophila wing imaginal discs Notch activation causes hyperplasia despite having localized inhibitory effects on proliferation. To understand te underlying mechanisms we have used genomic strategies to identify the Notch...
ORGANISM(S): Drosophila melanogaster 
2013-12-31 | E-GEOD-41428 | biostudies-arrayexpress
GenomicsDistribution of Drosophila insulator protein BEAF-32 in Wing imaginal tissue (Wildtype) [ChIP-seq]
Chromatin insulators are DNA protein complexes that mediate inter and intra chromosomal interactions. Boundary Element Associated Factor- 32 (BEAF-32) is an insulator protein predominantly found near gene promoters and thought to play a role in gene expression. We find that mutations in BEAF-32 are ...
ORGANISM(S): Drosophila melanogaster 
2012-07-05 | E-GEOD-36735 | biostudies-arrayexpress
TranscriptomicsGeometric control of the coronary artery endothelial cell transcriptome following standard growth condition
Analysis of the effects of cell shape on human coronary artery endothelial cell transcription. The hypothesis is that defined alterations in endothelial cell shape uniquely affect the endothelial transcriptome. Human coronary artery endothelial cells were plated onto spatially defined micropatterns...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-43349 | biostudies-arrayexpress
TranscriptomicsGeometric control of the coronary artery endothelial cell transcriptome following serum starvation
Analysis of the effects of cell shape on human coronary artery endothelial cell transcription. The hypothesis is that defined alterations in endothelial cell shape uniquely affect the endothelial transcriptome. Human coronary artery endothelial cells were plated onto spatially defined micropatterns...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-44167 | biostudies-arrayexpress
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