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Since the discovery of radial glia as the source of neurons, their heterogeneity in regard to neurogenesis has been described by clonal and time-lapse analysis in vitro. However, the molecular determinants specifying neurogenic radial glia differently from radial glia that mostly self-renew remain i...
ORGANISM(S): Mus musculus 
Evolution of the mammalian brain encompassed a remarkable increase in size of cerebral cortex, including tangential and radial expansion, but the mechanisms underlying these key parameters are still largely unknown. Here, we identified the novel DNA associated protein TRNP1 as a regulator of cerebra...
ORGANISM(S): Mus musculus 
A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex
A novel population of Hopx-dependent human-like basal radial glial cells in the developing mouse neocortex
Biallelic null variants in PNPLA8 cause microcephaly through the reduced abundance of basal radial gliaナカセンセイキニュウ
A specific subpopulation of neural progenitor cells, the basal radial glial cells (bRGCs) of the outer subventricular zone (OSVZ), are thought to have a key role in the evolutionary expansion of the mammalian neocortex. In the developing lissencephalic mouse neocortex, bRGCs exist at low abundance a...
ORGANISM(S): Mus musculus 
2018-10-10 | GSE121008 | GEO
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