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MetabolomicsLeptin increases hepatic triglyceride export via a vagal mechanism in humans
Recombinant human leptin (metreleptin) reduces hepatic lipid content in patients with lipodystrophy and overweight patients with non-alcoholic fatty liver disease and relative hypoleptinemia independent of its anorexic action. In rodents, leptin signaling in the brain increases very-low-density lipo...
2023-06-07 | MTBLS4231 | MetaboLights
TranscriptomicsSilencing of GATA3 defines a novel stem cell like subgroup of ETP-ALL
Genome wide expression profiling was used to detect cases of adult T-ALL lacking GATA3 expression. GATA3low T-ALL exhibited enrichment of myeloid/lymphoid progenitor (MLP) and granulocyte/monocyte progenitor (GMP) genes, while T-cell specific signatures were downregulated. Among upregulated genes FL...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-GEOD-78132 | biostudies-arrayexpress
TranscriptomicsAnalysis of global gene expression of a human T-ALL cell lines, comparing GATA3low ETP-ALL (i.e. PER-117) and "typical" T-ALL
Cell lines representing human T-ALL were analyzed to compare GATA3low ETP-ALL (i.e. PER-117) with "typical" T-ALL. Moreover, changes in global gene expression were assessed comparing GATA3low ETP-ALL (i.e. PER-117) and GATA3high ETP-ALL (i.e. Loucy) upon treatment with Decitabine, a hypome...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-GEOD-78166 | biostudies-arrayexpress
UnknownPerceiving societal pressure to be happy is linked to poor well-being, especially in happy nations.
Not available
S-EPMC8854619 | biostudies-literature
UnknownComparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis.
Not available
S-EPMC6824232 | biostudies-literature
UnknownAssociation of Social Determinants of Health with Time to Diagnosis and Treatment Outcomes in Idiopathic Subglottic Stenosis.
Not available
S-EPMC8762607 | biostudies-literature
UnknownCharacteristics and outcomes of SARS-CoV-2 breakthrough infections among double-vaccinated and triple-vaccinated patients with inflammatory rheumatic diseases.
Not available
S-EPMC10111193 | biostudies-literature
UnknownA multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.
Not available
S-EPMC8742248 | biostudies-literature
UnknownThe Psychological Science Accelerator's COVID-19 rapid-response dataset.
Not available
S-EPMC9918828 | biostudies-literature
UnknownEffect of Sacubitril/Valsartan vs Standard Medical Therapies on Plasma NT-proBNP Concentration and Submaximal Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction: The PARALLAX Randomized Clinical Trial.
Not available
S-EPMC8596197 | biostudies-literature
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