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MetabolomicsEFFECT OF DIFFERENT POOLED QC SAMPLES ON DATA QUALITY DURING AN INTER-BATCH EXPERIMENT IN UNTARGETED UHPLC-HRMS ANALYSIS ON TWO DIFFERENT MS PLATFORMS
Quality control (QC) samples are commonly used in metabolomics approaches for three main reasons: (i) the initial conditioning of the column; (ii) the correction of analytical drift especially between batches; and (iii) the evaluation of measurement precision. In practice there are several ways to p...
2026-02-04 | MTBLS10568 | MetaboLights
MetabolomicsAddressing batch effects in large-scale metabolomics with augmented experimental design and meta-analysis (Part 1)
Not available
ORGANISM(S): Caenorhabditis elegans 
ST002095 | MetabolomicsWorkbench
MetabolomicsAddressing batch effects in large-scale metabolomics with augmented experimental design and meta-analysis (Part 2)
Not available
ORGANISM(S): Caenorhabditis elegans 
ST002096 | MetabolomicsWorkbench
MetabolomicsAlignment and Analysis of a Disparately Acquired Multi-Batch Metabolomics Study of Maternal Pregnancy Samples (Part 1)
Not available
ORGANISM(S): Homo sapiens 
ST002134 | MetabolomicsWorkbench
MetabolomicsAlignment and Analysis of a Disparately Acquired Multi-Batch Metabolomics Study of Maternal Pregnancy Samples. (Part 2)
Not available
ORGANISM(S): Homo sapiens 
ST002135 | MetabolomicsWorkbench
MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
MetabolomicsOVCAR-3 spheroid-derived cells display distinct metabolic profiles
Recently, multicellular spheroids were isolated from a well-established epithelial ovarian cancer cell line, OVCAR-3, and were propagated in vitro. These spheroid derived cells displayed numerous hallmarks of cancer stem cells, which are chemo and radioresistant cells thought to be a significant cau...
2015-01-08 | MTBLS152 | MetaboLights
ProteomicsReprocessed dataset with Skyline Batch: Extending the limits of quantitative proteome profiling with data-independent acquisition and application to acetaminophen treated 3D liver microtissues
The data set represents a fair comparison of shotgun proteomics with HRM (swath type DIA). Additionally, a human liver microtissue was profiled with HRM. REPROCESSING METHODS: Skyline Batch is a newly developed Windows forms application that enables easy and consistent reprocessing of data with Skyl...
ORGANISM(S): Homo Sapiens 
2021-11-12 | PXD029663 | panorama
ProteomicsReprocessed dataset with Skyline Batch: SWATH Analysis of Yeast Proteome over Time in Response to Osmotic Stress
SWATH analysis of Yeast Proteome over time in response to Osmotic Stress. We sampled cell cultures in biological triplicates at six time points following the application of osmotic stress and acquired single injection DIA datasets on a high-resolution 5600 tripleTOF instrument operated in SWATH mode...
ORGANISM(S): Saccharomyces Cerevisiae 
2021-11-12 | PXD029665 | panorama
MetabolomicsA Bidirectional Regulatory ACLY-NLRP3 Axis Integrates Metabolic and Inflammatory Signaling to Control NLRP3 Inflammasome Activation

The NLRP3 inflammasome is critical for host defense against bacterial infection and is involved in the pathogenesis of various inflammatory diseases. The aggregation of its sensor protein NLRP3 is a pivotal checkpoint for inflammasome activation. Howev...

2026-01-07 | MTBLS13400 | MetaboLights
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