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TranscriptomicsDelineation of diverse macrophage activation programs in response to intracellular parasites and cytokines
To provide a global perspective on the relationships between macrophage activation programs and to understand how certain pathogens circumvent them, we used transcriptional profiling by genome wide microarray analysis to compare the responses of mouse macrophages following exposure to the intracellu...
ORGANISM(S): Mus musculus 
2010-04-13 | E-GEOD-20087 | biostudies-arrayexpress
TranscriptomicsExperimental Malaria Infection Triggers Early Expansion of Natural Killer Cells - NK cell response
In order to gain a better understanding of gene expression during early malaria infection, we conducted microarray analysis of early blood responses in mice infected with erythrocytic stage Plasmodium chabaudi. Immediately following infection, we observed coordinated and sequential waves of immune ...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12727 | biostudies-arrayexpress
TranscriptomicsExperimental Malaria Infection Triggers Early Expansion of Natural Killer Cells
In order to gain a better understanding of gene expression during early malaria infection, we conducted microarray analysis of early blood responses in mice infected with erythrocytic stage Plasmodium chabaudi. Immediately following infection, we observed coordinated and sequential waves of immune ...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-12249 | biostudies-arrayexpress
TranscriptomicsGene expression patterns of biopsies from a colonoscopy taken in 2008 of an ulcerative colitis patient infected with Trichuris trichiura
Helminth infection may have the potential to suppress intestinal inflammation in inflammatory bowel diseases. Ulcerative colitis is more common in developed countries than in developing countries endemic for helminth infections. There are animal models, as well as clinical trials, suggesting therape...
ORGANISM(S): Homo sapiens 
2010-11-20 | E-GEOD-25276 | biostudies-arrayexpress
TranscriptomicsMolecular signatures of mucosal immunity that distinguish HIV controllers from non-controllers
HIV â??controllersâ?? are individuals infected with the human immunodeficiency virus, type I (HIV) who maintain long-term control of viremia without antiviral therapy and who usually do not develop the acquired immune deficiency syndrome (AIDS). In this study, we have used oligonucleotide expression...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-20075 | biostudies-arrayexpress
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