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TranscriptomicsHost and pathogen interaction: time course [C. albicans]
The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fis...
ORGANISM(S): Candida albicans 
2013-08-26 | E-GEOD-32117 | biostudies-arrayexpress
TranscriptomicsFinal efficacy and biomarker analysis of the sorafenib arm of the BATTLE (Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination) trial
Purpose: To determine the 8-week disease control rate (DCR) of sorafenib monotherapy in patients with advanced non-small-cell lung cancer (NSCLC) in the BATTLE trial. Methods: Patients with pre-treated NSCLC consented to baseline biopsies for pre-specified biomarkers assessment and biomarker discove...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-31428 | biostudies-arrayexpress
TranscriptomicsChemorefractory non-small cell lung cancer gene expression profiles from the Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE) trial
This SuperSeries is composed of the following subset Series: GSE27389: Substitutions in the KRas oncogene determine protein behavior: Implications for signaling and clinical outcome. GSE31428: Final efficacy and biomarker analysis of the sorafenib arm of the BATTLE (Biomarker-Integrated Approaches o...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-31437 | biostudies-arrayexpress
TranscriptomicsHost and pathogen interaction: time course [zebrafish]
The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fis...
ORGANISM(S): Danio rerio 
2013-08-26 | E-GEOD-32118 | biostudies-arrayexpress
UnknownThe oncogenic role of MUC12 in RCC progression depends on c-Jun/TGF-β signalling.
Not available
S-EPMC7412406 | biostudies-literature
UnknownQuantitative proteome profiling of C. burnetii under tetracycline stress conditions.
Not available
S-EPMC3306420 | biostudies-literature
UnknownDGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling.
Not available
S-EPMC7367757 | biostudies-literature
UnknownMay God Guide Our Guns : Visualizing Supernatural Aid Heightens Team Confidence in a Paintball Battle Simulation.
Not available
S-EPMC6132840 | biostudies-literature
UnknownBATTLE: Genetically Engineered Strategies for Split-Tunable Allocation of Multiple Transgenes in the Nervous System.
Not available
S-EPMC7322263 | biostudies-literature
TranscriptomicsAn epithelial-mesenchymal transition (EMT) gene signature predicts resistance to erlotinib and PI3K pathway inhibitors and identifies Axl as a novel EMT marker in non-small cell lung cancer.
Epithelial/mesenchymal transition (EMT) is associated with loss of cell adhesion molecules, such as E-cadherin, and increased invasion, migration, and proliferation in epithelial cancers. In non-small cell lung cancer (NSCLC), EMT is associated with greater resistance to EGFR inhibitors. However, it...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-33072 | biostudies-arrayexpress
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