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TranscriptomicsTranscription profiling of tumors from the melanoblastoma bearing Libechov Minipig (MeLiM) model at 8 to 91 days after birth
Spontaneous regression is a well defined phenomenon commonly observed in human melanoma in its partial histopathological form but sporadically in its complete expression. Molecular mechanisms which might be involved in spontaneous regression are poorly understood so far. The Melanoblastoma bearing L...
ORGANISM(S): Sus scrofa 
2008-09-10 | E-MEXP-1152 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HEK293 cells transfected with CavB4 or CavB4-R482X mutant cDNA
Calcium channel B subunits (CavB) are mainly recognized for their contribution as regulatory subunits in modulating biophysical and trafficking channel properties. Here, we report for a novel function of the neuronal auxiliary CavB4 subunit in nuclear localization and transcriptional activity. In CA...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-MEXP-1165 | biostudies-arrayexpress
MetabolomicsOxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients' tumours, metastasis-derived patient-derived xenografts (PDX) and isogenic cell line...
2023-06-27 | MTBLS3342 | MetaboLights
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