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Background:; Plants are sessile and therefore have developed mechanisms to adapt to their environment, including the soil mineral nutrient composition. Ionomics is a developing functional genomics strategy designed to rapidly identify the genes and gene networks involved in regulating how plants acq...
ORGANISM(S): Arabidopsis thaliana 
ABSTRACT: Sphingolipid synthesis is initiated by condensation of serine with palmitoyl-CoA to produce 3-ketodihydrosphinganine (3-KDS), which is subsequently reduced by a 3-KDS reductase to dihydrosphinganine (DHS). Serine palmitoyltransferase was recently shown to be essential for plant viability,...
ORGANISM(S): Arabidopsis thaliana 
ABSTRACT; Molybdenum (Mo) is an essential micronutrient for plants, serving as a cofactor for enzymes involved in nitrate assimilation, sulfite detoxification, abscisic acid biosynthesis and purine degradation. Here we show that natural variation in shoot Mo content across 92 Arabidopsis thaliana a...
ORGANISM(S): Arabidopsis thaliana 
Understanding the mechanism of cadmium (Cd) accumulation in plants is important to help reduce its potential toxicity to both plants and humans through dietary and environmental exposure. Here, we report on a study to uncover the genetic basis underlying natural variation in Cd accumulation in a wor...
ORGANISM(S): Arabidopsis thaliana 
Concentration- and time- response and human lower EpiAveolar™ respiratory tract tissues comparison of transcriptional responses following 12-day exposure with different test materials. Differential expression and pathway analyses were performed to estimate the lowest transcriptional point of depar...
ORGANISM(S): Homo sapiens 
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