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TranscriptomicsMechanism and cellular actions of the potent AMPK inhibitor BAY-3827
Inhibition of AMP-activated protein kinase (AMPK) is increasingly being explored for its therapeutic potential in some diseases, including certain types of cancers. However, AMPK-inhibitory tool compounds have largely been limited to compound C/dorsomorphin and SBI-0206965, both of which display num...
ORGANISM(S): Mus musculus 
2025-07-28 | GSE290022 | GEO
GenomicsMechanism and cellular actions of the potent AMPK inhibitor BAY-3827
Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827
PRJNA1225752 | ENA
UnknownMechanism and cellular actions of the potent AMPK inhibitor BAY-3827.
Not available
S-EPMC12372887 | biostudies-literature
UnknownBAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation.
Not available
S-EPMC10778976 | biostudies-literature
UnknownNTRK1 knockdown induces mouse cognitive impairment and hippocampal neuronal damage through mitophagy suppression via inactivating the AMPK/ULK1/FUNDC1 pathway.
Not available
S-EPMC10618268 | biostudies-literature
UnknownComparison of the Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Cardiac Fibroblast Properties.
Not available
S-EPMC12564173 | biostudies-literature
UnknownAMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death.
Not available
S-EPMC11043078 | biostudies-literature
UnknownMetformin Enhances the Chemosensitivity of Gastric Cancer to Cisplatin by Downregulating Nrf2 Level.
Not available
S-EPMC12014253 | biostudies-literature
ProteomicsAMPK activation promotes transcriptional activation of TFEB through its dephosphorylation
Transcription Factor EB (TFEB) is a critical regulator of lysosomal biogenesis, autophagy and energy homeostasis through regulating expression of genes belonging to the Coordinated Lysosomal Expression and Regulation network. Recently, AMP-activated protein kinase (AMPK) was reported to phosphorylat...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-11 | PXD055410 | Pride
Bay-3827  coordinated lysosomal expression and regulation  mk-8722  reversible phosphorylation  mtor  tfe3 
UnknownA Skeletal Muscle-Mediated Anticontractile Response on Vascular Tone: Unraveling the Lactate-AMPK-NOS1 Pathway in Femoral Arteries.
Not available
S-EPMC11577611 | biostudies-literature
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