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ProteomicsMolecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus
We use hydrogen-deuterium exchange mass spectrometry (HDX-MS) to analyse the effects of S. aureus leucotoxins binding to the atypical chemokine receptor ACKR1 on receptor's structure and dynamics.
ORGANISM(S): Homo sapiens (Human) Staphylococcus aureus subsp. aureus NN50 
2021-11-03 | PXD027043 | Pride
Host-pathogen interactions Structural mass spectrometry Pharmacology Gpcr 
UnknownNeurocognitive deficits related to poor decision making in people behind bars.
Not available
S-EPMC3985492 | biostudies-literature
TranscriptomicsRegulation of NUMB alternative splicing by RBM5, RBM6 and RBM10 controls cancer cell proliferation
RBM5, a regulator of alternative splicing of apoptotic genes, and its close homologues, RBM6 and RBM10, are RNA binding proteins frequently deleted or mutated in lung cancer. We report that RBM5/6 and RBM10 antagonistically regulate the proliferative capacity of cancer cells and display distinct pos...
ORGANISM(S): Homo sapiens 
2013-12-20 | E-GEOD-47431 | biostudies-arrayexpress
TranscriptomicsRegulation of NUMB alternative splicing by RBM5, RBM6 and RBM10 controls cancer cell proliferation (CLIP-Seq)
RBM5, a regulator of alternative splicing of apoptotic genes, and its close homologues, RBM6 and RBM10, are RNA binding proteins frequently deleted or mutated in lung cancer. We report that RBM5/6 and RBM10 antagonistically regulate the proliferative capacity of cancer cells and display distinct pos...
ORGANISM(S): Homo sapiens 
2013-12-20 | E-GEOD-48066 | biostudies-arrayexpress
UnknownA reexamination of the evidence for the somatic marker hypothesis: what participants really know in the Iowa gambling task.
Not available
S-EPMC528759 | biostudies-literature
TranscriptomicsMicroarray analysis of microRNA expression in cutaneous squamous cell carcinoma
MicroRNAs (miRNAs) are a novel class of short RNAs which have shown to be dysregulated in a variety of cancers including squamous cell carcinoma (SCC) of the head&neck. Microarray based miRNA expression profiles of cutaneous SCC (cSCC) however have not been investigated so far. Seven patients with c...
ORGANISM(S): Homo sapiens 
2012-10-08 | E-GEOD-34536 | biostudies-arrayexpress
TranscriptomicsComparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic naevi
Perturbations in microRNA (miRNA) expression profiles has been reported for cutaneous malignant melanoma (CMM). With regards to a rapidly growing number of newly discovered miRNA sequences, the availability of up-to-date miRNA expression profiles for primary cutaneous malignant melanoma (PCMM), cuta...
ORGANISM(S): Homo sapiens 
2012-11-02 | E-GEOD-34460 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of microRNA expression in basal cell carcinoma
Perturbations in the expression profiles of microRNAs (miRNAs) have been reported for a variety of different cancers. Basal cell carcinoma (BCC) of the skin has not been systematically evaluated regarding differentially expressed miRNAs. Patients with BCC (n=7) were included in the study. Punch biop...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-34535 | biostudies-arrayexpress
UnknownTumor suppressor properties of the splicing regulatory factor RBM10.
Not available
S-EPMC4841610 | biostudies-literature
UnknownA Triadic Reflective-Impulsive-Interoceptive Awareness Model of General and Impulsive Information System Use: Behavioral Tests of Neuro-Cognitive Theory.
Not available
S-EPMC4845517 | biostudies-literature
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