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TranscriptomicsTranscription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice
Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration. Transcription factor Tcfap2c / TFAP2C has been described to be essential for primordial germ cell mainten...
ORGANISM(S): Mus musculus 
2014-01-30 | E-GEOD-45941 | biostudies-arrayexpress
UnknownPresynaptic dysfunction in CASK-related neurodevelopmental disorders.
Not available
S-EPMC7490425 | biostudies-literature
TranscriptomicsLimited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer’s disease
Transcriptome analysis of hippocampal RNA samples from wild-type, 5xFAD, 5xFAD;eIF2α+/S51A and eIF2α+/S51A mice Our transcriptome analyses showed clear transcriptional alterations in hippocampi of 5xFAD compared to wild type mice that were not corrected by the eIF2αS51A allele. Hemizygous 5xFAD mice...
ORGANISM(S): Mus musculus 
2013-09-10 | E-GEOD-50521 | biostudies-arrayexpress
TranscriptomicsDerivation and maintenance of murine trophoblast stem cells under defined conditions
Trophoblast stem (TS) cells are in vitro equivalents to the precursor cells of the placenta. In mice, TS cells can be derived either from polar trophectoderm (TE) of blastocyst outgrowths or from postimplantation extraembryonic ectoderm (ExE), originating from polar TE. Since their first successful ...
ORGANISM(S): Mus musculus 
2014-01-28 | E-GEOD-47719 | biostudies-arrayexpress
UnknownGenome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder.
Not available
S-EPMC4168827 | biostudies-literature
UnknownThe pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single cell resolution.
Not available
S-EPMC9452154 | biostudies-literature
UnknownHIGH GRADE GLIOMAS AND DIPG
Not available
S-EPMC4046287 | biostudies-literature
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