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ProteomicsMonitoring Biomarker Study in Becker Muscular Dystrophy using Data Independent Acquisition LC-MS/MS
Becker muscular dystrophy (BMD) is a rare and heterogenous form of dystrophinopathy caused by reduced expression of altered dystrophin protein. Gene therapies and exon-skipping therapies for the more severe form of dystrophinopathy, Duchenne muscular dystrophy (DMD), assume that disease progression ...
ORGANISM(S): Homo Sapiens 
2025-10-31 | PXD054253 | panorama
TranscriptomicsTranscription profiling of human muscle biopsies from Duchenne muscular dystrophy subjects treated with oxandrolone
Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were ...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-1764 | biostudies-arrayexpress
UnknownStructure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives.
Not available
S-EPMC3076632 | biostudies-literature
UnknownStructure-activity relationships of lipopolysaccharide sequestration in N-alkylpolyamines.
Not available
S-EPMC3699868 | biostudies-literature
UnknownStructure-based design of novel human Toll-like receptor 8 agonists.
Not available
S-EPMC4105021 | biostudies-literature
UnknownToll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines.
Not available
S-EPMC3577938 | biostudies-literature
TranscriptomicsSSH-PCR dehydrated supraoptic nucleus
The magnocellullar neurons (MCNs) of the supraoptic nucleus (SON) of the hypothalamus are the principle source of the neuropeptide hormone vasopressin (VP), which has a crucial role in osmoregulation. Physiological activation of the SON by dehydration results is a massive release of VP from stores i...
ORGANISM(S): Rattus norvegicus 
2010-06-30 | E-GEOD-3132 | biostudies-arrayexpress
TranscriptomicspCREB-dependent transcriptional activation is a mediator of molecular neuroadaptations induced by methamphetamine self-administration in the rat dorsal striatum
Neuroplastic changes in the dorsal striatum participate in the transition from casual drug use to habitual and compulsive drug taking. These alterations might also play a critical role in the development of methamphetamine (METH) addiction. Nevertheless, the molecular substrates that underlie habitu...
ORGANISM(S): Rattus norvegicus 
2012-05-31 | E-GEOD-38223 | biostudies-arrayexpress
UnknownLower vitamin D is associated with metabolic syndrome and insulin resistance in systemic lupus: data from an international inception cohort.
Not available
S-EPMC8487307 | biostudies-literature
UnknownDeterminants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds.
Not available
S-EPMC4191598 | biostudies-literature
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