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TranscriptomicsIntegrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
The saprophytic mold Aspergillus fumigatus produces small (2-3 µm) airborne spores (conidia) that can reach the lung alveoli upon inhalation. There, they encounter the surfactant-rich environment of the alveolar epithelium and initiate swelling and germination. Primary alveolar macrophages are essen...
ORGANISM(S): Homo sapiens 
2026-10-02 | E-MTAB-17130 | biostudies-arrayexpress
TranscriptomicsStimulation of Human and Rat Islet β-Cell Proliferation with Retention of Function by Nkx6.1
The homeodomain transcription factor Nkx6.1 plays an important role in pancreatic islet β-cell development, but its effects on adult β-cell function, survival, and proliferation are not well understood. In the present study, we demonstrated that treatment of primary rat pancreatic islets with a cy...
ORGANISM(S): Rattus norvegicus 
2010-05-18 | E-GEOD-13153 | biostudies-arrayexpress
UnknownGenomic surveillance of Canadian airport wastewater samples allows early detection of emerging SARS-CoV-2 lineages.
Not available
S-EPMC11532424 | biostudies-literature
UnknownLongitudinal Change in Adolescent Depression and Anxiety Symptoms from before to during the COVID-19 Pandemic.
Not available
S-EPMC9349954 | biostudies-literature
UnknownInfluence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest.
Not available
S-EPMC11264458 | biostudies-literature
UnknownTransforming jet flavour tagging at ATLAS.
Not available
S-EPMC12804921 | biostudies-literature
UnknownVitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI.
Not available
S-EPMC7032996 | biostudies-literature
UnknownCommon schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Not available
S-EPMC5918692 | biostudies-literature
UnknownSafety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial.
Not available
S-EPMC7445431 | biostudies-literature
UnknownEffect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial.
Not available
S-EPMC4123233 | biostudies-literature
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