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TranscriptomicsGene regulation in ki-ras transfected murine fibroblasts
Ki-ras gene mutations are involved in the carcinogenesis of acute myeloid leukemia, melanoma and different carcinomas. In order to define potential mutation-specific therapeutic targets, expression profiling analyses were performed using stable transfected NIH3T3 cells carrying different ki-ras gene...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-8372 | biostudies-arrayexpress
TranscriptomicsGene expression profile of a murin neuroblastoma cell line infected with the prion strain 22L
The underlying pathogenic mechanisms of prion infection are not well characterized. To study the effect of prion infection on gene expression in neuronal cell cultures, a neuroblastoma (N2a) cell clone was infected with either the mouse adapted prion strain 22L or exposed to uninfected brain homogen...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-7119 | biostudies-arrayexpress
ProteomicsTECPR2 knock-in mice proteomics
Mutation in the gene encoding Tectonic -propeller repeat-containing repeat protein 2 (TECPR2) leads to hereditary sensory and autonomic neuropathy type 9 (HSAN9) which is a fatal complex neurodevelopmental and neurodegenerative disorder involving the sensory and peripheral nervous system. TECPR2 is ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-11-10 | PXD059099 | Pride
Bicap Endoip Hsan9 Microglia Tecpr2 
TranscriptomicsQuantification of regenerative potential in primary human mammary epithelial cells
We present an organoid regeneration assay in which freshly dissociated human mammary epithelial cells from healthy donors are grown in adherent/rigid or floating/compliant collagen I gels. In both conditions, luminal progenitors (CD49f+EpCAM+) form spheres, whereas basal cells (CD49fhiEpCAM-) genera...
ORGANISM(S): Homo sapiens 
2015-07-02 | E-GEOD-64248 | biostudies-arrayexpress
UnknownRedox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes.
Not available
S-EPMC10635655 | biostudies-literature
TranscriptomicsTranscription profiling and proteomic profiling of mouse hippocampus
We have correlated transciptomics, proteomics and toponomics analyses of hippocampus tissue of inbred C57/BL6 mice to analyse the interrelationship of expressed genes and proteins at different levels of organization. We find that transcriptome and proteome levels of function are highly conserved bet...
ORGANISM(S): Mus musculus 
2008-06-19 | E-GEOD-8239 | biostudies-arrayexpress
UnknownAbstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.
Not available
S-EPMC5435609 | biostudies-literature
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