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GenomicsDorsal dependent CBP binding on a genome wide scale
We find a high concordance between the binding of the Drosophila transcription factor Dorsal and the co-activator CBP during early embryogenesis. This relationship was furter examined by comparing CBP distribution in Drosophila embryos derived from wt and mutant flies lacking intranuclear Dorsal (gd...
ORGANISM(S): Drosophila melanogaster 
2012-06-28 | E-GEOD-34221 | biostudies-arrayexpress
TranscriptomicsA dominant-negative isoform of IKAROS expands primitive normal human hematopoietic cells
Human cord blood CD34+ cells transduced with control of IK6 lentivirus were transplanted into NSG mice. Control and IK6 transduced CD34+38- progeny were acquired 10 weeks later by FACS Comparison of control and IK6+ human CD34+38- progenitor cells
ORGANISM(S): Homo sapiens 
2014-09-14 | E-GEOD-60957 | biostudies-arrayexpress
TranscriptomicsDNA:RNA Immunoprecipitation and Tiling Microarray (DRIP-chip)
Experiment to obtain the genome-wide distribution of DNA:RNA hybrid prone loci in Saccharomyces cerevisiae by DNA:RNA immunoprecipitation and tiling microarray (DRIP-chip). Samples: wild type, Rnase H deletion mutant, hpr1 deletion mutant, sen1-1 temperature sensitive mutant.
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-06 | E-MTAB-2388 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast deletion mutants of putative protein complex members
A number of putative protein complexes have been selected for experimental validation by gene expression profiling of the individual deletion mutants of the respective protein complex members.
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-01 | E-TABM-654 | biostudies-arrayexpress
TranscriptomicsHP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster
Heterochromatin protein 1 (HP1) proteins are important regulators of heterochromatin mediated gene silencing and chromosome structure and it is well known as the reader of the heterochromatin mark methylation of histone H3 lysine 9 (H3K9me). In Drosophila three different histone lysine methyl transf...
ORGANISM(S): Drosophila melanogaster 
2012-12-21 | E-GEOD-38366 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast wild type and YJL103C deletion mutant during glucose starvation in a time series
Expression profiling of YJL103C deletion mutant compared to wild type during glucose starvation (4h, exponential phase; 24h, diauxic shift; 72h, post-diauxic growth; 144h, entry into stationary phase)
ORGANISM(S): Saccharomyces cerevisiae 
2008-01-01 | E-MEXP-769 | biostudies-arrayexpress
TranscriptomicsMRE11-RAD50-NBS1 activates Fanconi Anemia R-loop suppression at transcription-replication conflicts
Rad50 is a component of the conserved MRE11-RAD50-NBS1 (MRN) complex, which functions in genome stability and the cell’s ability to deal with stalled DNA replication forks. We identified Rad50 as a factor important for R-loop tolerance and thus mapped DNA:RNA hybrids in Rad50KO cells and compare the...
ORGANISM(S): Saccharomyces cerevisiae 
2019-10-31 | E-MTAB-7885 | biostudies-arrayexpress
UnknownTrial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
Not available
S-EPMC4872347 | biostudies-literature
TranscriptomicsTranscription profiling by array of Rhizobium leguminosarum bivar viciae strain Rlv3841 grown on pyruvate ammonia AMS with the addition of pea root washing
Rhizobium leguminosarum bivar viciae strain Rlv3841 was grown in the laboratory on pyruvate (10mM) ammonia (10mM) AMS. The effect of addition of pea root washing was compared to an untreated control.
ORGANISM(S): Rhizobium leguminosarum 
2010-10-02 | E-MEXP-2846 | biostudies-arrayexpress
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