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TranscriptomicsSingle-cell RNA-seq of intestinal γδ T cells from cIAP2-deficient and RORγt-Cre–mediated cIAP1 conditional knockout mice across developmental stages
This study investigates the post-thymic maturation and transcriptional programming of intestinal γδ T cells across early life. Single-cell RNA sequencing of FACS-sorted small-intestinal lamina propria γδ T cells was performed at four developmental stages: newborn, day 7, day 21, and post-weaning (da...
ORGANISM(S): Mus musculus 
2026-03-14 | E-MTAB-16692 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of murine γδT17 and γδT1 cells from the lamina propria and peripheral lymph nodes of wild-type mice
This experiment was designed to explore the transcriptional programs of γδT17 and γδT1 cells isolated from the lamina propria and peripheral lymph nodes. For this purpose, we sorted intestinal γδT17 (RORγtGFP+TbetAmCyan+) and γδT1 (TbetAmCyan+) cells, as well as γδT17 (RORγtGFP+) and γδT1 (TbetAmCya...
ORGANISM(S): Mus musculus 
2026-03-14 | E-MTAB-16691 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of murine γδT17 cells isolated from the lamina propria of Tbet-deficient mice
This experiment was designed to explore the biological relevance of the transcription factor Tbet in intestinal γδT17 cells. For this purpose, we crossed TbetF/F with RORγtCRE-R26LSLRFP mice, where RFP expression in the ROSA26 locus was induced by RORγt-driven Cre recombinase. We then sorted Tbet-de...
ORGANISM(S): Mus musculus 
2026-03-14 | E-MTAB-16689 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of murine γδT17 cells isolated from the lamina propria of wild-type mice at day 0 and day 7
This experiment was designed to gain mechanistic insight into the molecular changes underlying the differentiation of intestinal γδT17 cells during neonatal life. For this purpose, we sorted intestinal RORγt⁺ γδ T cells from day 0 and day 7 RORγtGFP+ mice and performed bulk RNA-seq.
ORGANISM(S): Mus musculus 
2026-03-14 | E-MTAB-16690 | biostudies-arrayexpress
UnknownIL-27 maintains cytotoxic Ly6C+ gamma delta T cells that arise from immature precursors
Not available
S-SCDT-10_1038-S44318-024-00133-1 | biostudies-other
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