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TranscriptomicsSuberoylanilide hydroxamic acid (SAHA) induces limited changes in the transcriptome of primary CD4+ T cells
This study evaluated primary CD4+ T cell gene expression treated with pharmacologically achievable concentration (340 nM) of SAHA for 24 hours in order to evaluate potential side effects of this compound in cells relevant to HIV infection. Analysis of human primary CD4+ T cells taken from 9 healthy ...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-41504 | biostudies-arrayexpress
TranscriptomicsCD4+ T cell gene expression in virologically suppressed HIV-infected patients during Maraviroc intensification therapy.
Analysis of CD4+ T cell gene expression changes after 4 and 24 weeks of Maraviroc administration relative to baseline in 25 immunodiscordant patients with viral suppression. Maraviroc elicited very modest changes in CD4+ T cell transcriptome. The goal of this study was to identify genes with a poten...
ORGANISM(S): Homo sapiens 
2014-04-16 | E-GEOD-56804 | biostudies-arrayexpress
OtherMixed effects of suberoylanilide hydroxamic acid (SAHA) on the host transcriptome and proteome and their implications for HIV reactivation from latency.
Data from ProteomeXchange, PXD ID: PXD002150. File: 14july14_saha_b_65.mzml. Published as part of Antiviral Res. 2015 Sep 3. pii: S0166-3542(15)00213-2 . From the Abstract: {{i}} ... We therefore utilized a combined analysis of effects of SAHA on the host transcriptome and proteome to dissect its m...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310023592 | GPMDB
Resource Reanalysis 
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