The study includes whole-genome bisulfite sequencing (WGBS) on 34 adipose
(7 MZ pairs, 6 DZ pairs and 8 singletons) and 27 blood (7 MZ pairs, 6 DZ
pairs and 1 singleton) DNA samples derived from a total of 43 female twins
belonging to the MuTHER/TwinsUK cohort. We generated 11.5 billion 100bp
paired...
Summary statistics for a multi-cohort epigenome-wide association study. This includes summary statistics (effect-size, standard error, p-value) for 470,000 methylation markers.
Overweight and obesity affect ~1.5 billion people worldwide, and are major risk factors for type-2 diabetes (T2D), cardiovascular disease and related metabolic and inflammatory disturbances.1,2 Although the mechanisms linking adiposity to its clinical sequelae are poorly understood, recent studies s...
