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ProteomicsN-terminal processing of CSP in P. falciparum salivary gland sporozoites
Salivary gland sporozoites of the malaria parasite Plasmodium express a major surface coat protein, CSP. The N-terminus of this protein is hypothesized to be enzymatically processed, revealing a Gln residue which is then enzymatically converted pyro-Glu. We analyzed P. falciparum salivary gland spor...
ORGANISM(S): Plasmodium falciparum NF54 
2025-05-07 | PXD052186 | Pride
Plasmodium malaria sporozoites 
ModelsSluka2016 - Acetaminophen metabolism
Sluka2016 - Acetaminophen metabolism Liver metabolism of Acetaminophen: Acetaminophen (APAP) is metabolized in the liver in both Phase I and Phase II reactions. Phase II reactions convert APAP to APAP-glucuronide and APAP-sulfate. Phase I reactions involve Cytochrome P450 mediated (mostly Cyp450-2E...
2024-09-02 | BIOMD0000000624 | BioModels
UnknownSynthesis of P-Stereogenic Benzoazaphosphole 1-Oxides via Alkynylation of P-Stereogenic ortho-Aurated and ortho-Iodo Phosphinic Amides.
Not available
S-EPMC6641963 | biostudies-literature
UnknownVaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes.
Not available
S-EPMC5047630 | biostudies-literature
UnknownSingle-dose CRISPR-Cas9 therapy extends lifespan of mice with Hutchinson-Gilford progeria syndrome.
Not available
S-EPMC6541418 | biostudies-literature
UnknownAutistic traits and individual brain differences: functional network efficiency reflects attentional and social impairments, structural nodal efficiencies index systemising and theory-of-mind skills.
Not available
S-EPMC7818759 | biostudies-literature
UnknownAdenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults.
Not available
S-EPMC3189181 | biostudies-literature
UnknownDNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity.
Not available
S-EPMC3573028 | biostudies-literature
UnknownCharacterization of the Epigenetic Changes During Human Gonadal Primordial Germ Cells Reprogramming.
Not available
S-EPMC5018215 | biostudies-literature
ModelsSluka2016 - Acetaminophen PBPK
Basic PBPK (Physiologically Based PharmacoKinetic) model of Acetaminophen. This is a basic model of Acetaminophen (APAP, Paracetamol) pharmacokinetics in humans. Many of the model parameters (compartment volumes, volumetric flow rates, etc.) are scaled allometrically based o...
2024-09-02 | BIOMD0000000619 | BioModels
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