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TranscriptomicsEffects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-81959 | biostudies-arrayexpress
MetabolomicsProlonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice
Emerging new evidence highlights the importance of prolonged daily fasting periods for the health and survival benefits of calorie restriction (CR) and time-restricted feeding (TRF) in male mice; however, little is known about the impact of these feeding regimens in females. We placed 14-month-old f...
2024-05-14 | MTBLS790 | MetaboLights
MetabolomicsUltra-High Mass Resolving Power, Mass Accuracy, and Dynamic Range MALDI Mass Spectrometry Imaging by 21-T FT-ICR MS

Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy and dynamic range. Fourier transform ion cyclotron resonance mass sp...

2022-01-28 | MTBLS3154 | MetaboLights
ProteomicsA microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - 3D PEG-CBF-0.5 MS
LC-MS/MS based analysis of murine PCOs growing in 3D PEG-CBF-0.5 hydrogels for four days.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-29 | PXD022520 | Pride
Ecm Pdac Organoids Syntheticmatrix 
ProteomicsA microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - CDM Sets
Cell-derived matrix (CDM) datasets from KPC-1 or HPDE cells after seven days of growth.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-11-29 | PXD022509 | Pride
Ecm Pdac Cancer Syntheticmatrix 
ProteomicsA microenvironment-inspired synthetic 3D model for pancreatic ductal adenocarcinoma organoids - IAC Sets
Integrin adhesion complex (IAC) datasets from KPC-1 and iKRAS cells after 3h or 12h of adhesion on a fibronectin pre-coated surface. IACs were isolated using previously established methods and IACs were investigated using LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-29 | PXD022487 | Pride
Tumour Organoids Syntheticmatrice Pdac 
TranscriptomicsA High-Fat Diet and NAD+ Rescue Premature Aging in Cockayne Syndrome
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in the genes encoding the DNA repair proteins CSA or CSB. Csbm/m mice were given a high-fat, caloric-restricted or resveratrol-supplemented diet. The high-fat diet rescued the p...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-62194 | biostudies-arrayexpress
TranscriptomicsRole of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-12-02 | E-GEOD-52279 | biostudies-arrayexpress
ProteomicsProteogenomics Connects Somatic Mutations to Signalling in Breast Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084248 | MassIVE
ProteomicsProteogenomic characterization of human colon and rectal cancer
Explore This Study at the NCI Proteomic Data Commons

Zhang, B., et al., Nature (2014) do...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-26 | MSV000084238 | MassIVE
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