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TranscriptomicsTreatment of human monocyte-derived dendritic cells with Saccaromyces cerevisiae in exponential growth phase
In vitro experiment of stimulation of monocyte-derived dendritic cells with Saccaromyces cerevisiae in exponential growth phase. This experiment was performed to verify the comparability of microarray experiments using a pathway based logic (Beltrame et al., PLoS 2009) by comparing the analysis of t...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-13901 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse myotubes infected with PGCalpha
Various studies have shown that aerobic exercise can prevent or alleviate cancer-induced muscle wasting. To reproduce at least partially in vitro some molecular differences of aerobic muscle exercise that are independent from systemic inflammation or the hormonal milieu, we infected fully different...
ORGANISM(S): Mus musculus 
2019-11-17 | E-MTAB-8457 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of ovarian cancer samples with different grades
We have previously demonstrated (Calura E et al., 2013) that different epithelial ovarian cancer (EOC) histotypes have different, defined characteristics at the microRNA level, which might highlight a different originating tissue for the disease. From these results we have invesigated whole-genome g...
ORGANISM(S): Homo sapiens 
2014-12-12 | E-MTAB-1814 | biostudies-arrayexpress
TranscriptomicsGenotyping of human clear cell renal carcinoma tissue and matched normal blood samples using Affymetrix GeneChip Human Mapping 50K Array Hind 240 to identify copy number changes and regions of loss of heterozygosity
We performed a genome-wide assessment of copy number alterations and LOH regions in a collection of cleal cell renal carcinoma tissue samples as compared to matched normal blood samples. Affymetrix GeneChip Human Mapping 100K SNP arrays were used. This experiment includes GeneChip Human Mapping 50K ...
ORGANISM(S): Homo sapiens 
2008-01-16 | E-TABM-283 | biostudies-arrayexpress
TranscriptomicsGenotyping of human clear cell renal carcinoma tissue and matched normal blood samples using Affymetrix GeneChip Human Mapping 50K Array Xba 240 to identify copy number changes and regions of loss of heterozygosity
We performed a genome-wide assessment of copy number alterations and LOH regions in a collection of clear cell renal carcinoma tissue samples as compared to matched normal blood samples. Affymetrix GeneChip Human Mapping 100K SNP arrays were used. This experiment includes GeneChip Human Mapping 50K ...
ORGANISM(S): Homo sapiens 
2008-01-16 | E-TABM-284 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of mixoid liposarcoma cell lines sensitive and resistant to trabectidin
This investigation aims at identifying differentially expressed miRNA between two cell lines, MLS 402-91 (sensitive to trabectidin) and MLS 402-91/ET (resistant to trabectidin).
ORGANISM(S): Homo sapiens 
2012-06-05 | E-MTAB-695 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of rats treated with VX-765 and Anakinra
Various studies showed a significant production/release of IL-1 beta following status epilepticus (SE) and during epileptogenesis. We studied the role of this cytokine in the epileptogenic process by blocking its production and downstream effects in vivo in a model of acquired epilepsy following SE ...
ORGANISM(S): Rattus norvegicus 
2013-12-10 | E-MTAB-1567 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiling of ovary cell tumors and HOSE cells
In order to determine the difference at the microRNA level of different ovarian tumor histotypes, we have performed a whole miRNA screening on 183 patients of grade 1 ovarian cancer. Additionally, we compared the miRNA profile of tumors with standard ovarian epithelial cells (HOSE).
ORGANISM(S): Homo sapiens 
2013-06-17 | E-MTAB-1067 | biostudies-arrayexpress
TranscriptomicsTime course experiment of dendritic cells exposed to curdlan
Human monocyte derived dendritic cells were exposed to the pure Dectin-1 agonist Curdlan to analyze the early transcriptional activation of DCs. This experiment is related to E-MTAB-750.
ORGANISM(S): Homo sapiens 
2012-08-28 | E-MTAB-1213 | biostudies-arrayexpress
TranscriptomicsStimulation of dendritic cells with cell wall components
In order to dissect the response from different fungal cell wall components, monocyte-derived dendritic cells obtained from healthy donors were collected and either left untreated, or treated for four hours with either mannan, zymosan, curdlan, whole yeast, or yeast spores. This experiment is relat...
ORGANISM(S): Homo sapiens 
2012-08-28 | E-MTAB-750 | biostudies-arrayexpress
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