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TranscriptomicsCopy number variation in the bovine genome
Copy number variations (CNVs), which represent a significant source of genetic diversity in mammals, are currently being associated with phenotypes of clinical relevance, mostly in humans and mice. Notwithstanding, little is known about the extent of CNV that contributes to genetic variation in catt...
ORGANISM(S): Bos taurus 
2010-04-22 | E-GEOD-18174 | biostudies-arrayexpress
TranscriptomicsHeart-muscle expression ratios in pig obtained by 454-sequencing, iTRAQ-based proteomics and cDNA microarrays
The recent development within high-throughput technologies for expression profiling has allowed for parallel analysis of transcriptomes and proteomes in biological systems such as comparative analysis of transcript and protein levels of tissue regulated genes. Until now, such studies of have only in...
ORGANISM(S): Sus scrofa 
2009-01-22 | E-GEOD-10122 | biostudies-arrayexpress
TranscriptomicsA Snapshot of Copy Number Variation in the pig genome
Recents studies in mammalian genomes have uncovered the extent of copy number variation (CNV) that contributes to phenotypic diversity, including health and disease status. Here we report the first glimpse of CNVs in the pig genome covering part of the chromosomes 4, 7, 14 and 17 already sequenced a...
ORGANISM(S): Sus scrofa 
2010-06-21 | E-GEOD-10753 | biostudies-arrayexpress
TranscriptomicsThe regenerative response in the pig liver remnant varies with the degree of resection and rise in portal pressure.
Following parenchymal loss, the liver regenerates restoring normal mass and metabolic function. Prevailing theories on triggering events leading to regeneration include humoral, metabolic and flow-mediated mechanisms, the latter emphasizing the importance of shear stress mediated nitric oxide (NO) r...
ORGANISM(S): Sus scrofa 
2008-01-14 | E-GEOD-6860 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling of 27k cDNAs in 23 healthy porcine tissues
Background. Gene expression microarrays have been intensively applied to screen for genes involved in specific biological processes of interest such as diseases or responses to environmental stimuli. For mammalian species, cataloging of the global gene expression profiles in large tissue collections...
ORGANISM(S): Sus scrofa 
2007-11-21 | E-GEOD-4918 | biostudies-arrayexpress
TranscriptomicsMicroRNA identity and abundance in porcine skeletal muscles determined by deep sequencing
MicroRNAs (miRNA) are short single-stranded RNA molecules that regulate gene expression post-transcriptionally by binding to complementary sequences in the 3' untranslated region (3' UTR) of target mRNAs. MiRNAs participate in the regulation of myogenesis, and identification of the complete set of m...
ORGANISM(S): Sus scrofa 
2009-11-24 | E-GEOD-14584 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in liver of pigs with extreme high and low levels of androstenone.
ABSTRACT: BACKGROUND: Boar taint is the unpleasant odour and flavour of the meat of uncastrated male pigs that is primarily caused by high levels of androstenone and skatole in adipose tissue. Androstenone is a steroid and its levels are mainly genetically determined. Studies on androstenone metabol...
ORGANISM(S): Sus scrofa 
2008-08-17 | E-GEOD-11073 | biostudies-arrayexpress
TranscriptomicsEarly pig response to experimental infection with Actinobacillus pleuropneomuniae
The objective of this study was to identify porcine genes which expression was affected by experimental infection with A. pleuropneumoniae within 24 hours after experimental challenge. Microarray experiments were conducted to reveal genes being significantly differentially expressed in infected vers...
ORGANISM(S): Sus scrofa 
2010-06-11 | E-GEOD-4577 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in testis of pigs with extreme high and low levels of androstenone.
Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis. Here we use microarrays to study the expression of thousands of genes simultaneously in testis of high and low a...
ORGANISM(S): Sus scrofa 
2007-11-26 | E-GEOD-7409 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of boars with high and low skatole levels
Skatole is one of the compounds causing boar taint in meat of uncastrated male pigs. This study focuses on differences in gene expression of 50 Danish Landrace boars with high and low skatole levels. The animals were divided into 2 groups based on the skatole measurements, with animals having a skat...
ORGANISM(S): Sus scrofa 
2015-06-15 | E-GEOD-29974 | biostudies-arrayexpress
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