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TranscriptomicsPre-metastatic expression array day 7
To follow the earliest transcriptional changes in pre-metastatic tissues, we orthotopically injected 4T1 cells into the mammary fat pad of female nude mice. Control mice were orthotopically injected with PBS. 7 days post tumor engraftment, the mice were sacrificed and thoroughly perfused with ice co...
ORGANISM(S): Mus musculus 
2011-07-24 | E-GEOD-30885 | biostudies-arrayexpress
TranscriptomicsComparison of human embroynic stem cell derived vascular cells to mature human vascular and hematopoietic cells
The pathways involved in hierarchical differentiation of human embryonic stem cells (hESC) into abundant and durable endothelial cells (EC) are unknown. We employed an EC-specific VE-cadherin promoter driving GFP (hVPr-GFP) to screen for factors that augmented yields of vascular-committed ECs from h...
ORGANISM(S): Homo sapiens 
2010-01-05 | E-GEOD-19735 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of various cell types isolated from pancreatic islet grafts in Id1/Id3 deficient and wild type mice
To gain insights into the genetic program activated within the distinct vascular and inflammatory transplant microenvironments in Id1/Id3 deficient and WT mice, we performed a series of gene screening experiments using RNA from total graft tissue as well as from myeloid and endothelial (i.e., CD31+ ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-TABM-355 | biostudies-arrayexpress
TranscriptomicsId proteins synchronize stemness and anchorage to the niche of neural stem cells
Stem cell functions require activation of stem cell-intrinsic transcriptional programs as well as intimate extracellular interactions with a niche microenvironment. How the core pluripotency transcriptional machinery controls residency of stem cells in the niche microenvironment is unknown. Here we ...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-36488 | biostudies-arrayexpress
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