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MetabolomicsSerum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer (Untargeted assay)

BACKGROUND: Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer (PCa) are current clinical challenges.

METHODS: The serum metabolites of 20 healthy individuals and patients with prosta...

2023-04-17 | MTBLS6039 | MetaboLights
MetabolomicsSerum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer (Targeted organic acid assay)

BACKGROUND: Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are current clinical challenges.

METHODS: The serum metabolites of 20 healthy individuals and patients with prostat...

2023-04-17 | MTBLS6038 | MetaboLights
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
MetabolomicsComprehensive plasma metabolomics and lipidomics based management of benign and malignant solitary pulmonary nodules
Not available
ORGANISM(S): Homo sapiens 
ST001937 | MetabolomicsWorkbench
Metabolomicsmetabolome in a group of AA and EA matched pairs of prostate cancer (PCa) and benign adjacent tissues
Not available
ORGANISM(S): Homo sapiens 
ST000784 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human tissue samples to identify novel genes associated with malignant melanoma but not benign melanocytic lesions
A number of melanoma specific genes were identified to differentiate clinical relevant tissue samples containing benign from malignant melanocytes. Experiment Overall Design: 7 normal skin, 18 nevi and 45 melanoma samples
ORGANISM(S): Homo sapiens 
2007-09-06 | E-GEOD-3189 | biostudies-arrayexpress
OtherDifferentially expressed proteins in malignant and benign adrenocortical tumors.
Data from ProteomeXchange, PXD ID: PXD000604. Experiment: Exp1, file: folder summary. Published as part of PLoS One. 2014 Feb 3;9(2):e87951 . From the Abstract: {{i}} We have compared the microsomal protein composition of eight malignant and six benign adrenocortical tumors with proteomic methods ....
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210025579 | GPMDB
Resource Reanalysis 
TranscriptomicsOncomiRs like let-7 and miR-21 are deregulated in two types of benign tumors: Fibroadenoma and Fibroadenomatosis
In this study we have preformed miRNA and mRNA expression profiling of benign breast tumors, breast cancers, and normal breast tissue. We have identified cancer-related miRNAs in benign tumors, with their deregulation similar to that in cancer tissue. In addition we have performed miRNA-mRNA correla...
ORGANISM(S): Homo sapiens 
2011-12-02 | E-MTAB-779 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human malignant or benign breast cancer tumors to identify genes that present a differential expression between the two types of lesion
Background. Although gene expression arrays have been used to generate molecular predictors of relapse and drug sensitivity in breast cancer, no large study describes genes and exons differentially expressed between breast cancer and benign lesions.

Methods. One hundred and sixty-five tumour...
ORGANISM(S): Homo sapiens 
2009-12-30 | E-TABM-609 | biostudies-arrayexpress
TranscriptomicsPreoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology
BACKGROUND: Following fine needle aspiration, 15-30% of thyroid nodules are not clearly benign or malignant. These cytologically indeterminate nodules are often referred for diagnostic surgery, though most prove benign. A novel diagnostic test measuring the expression of 167 genes has shown promise ...
ORGANISM(S): Homo sapiens 
2012-06-24 | E-GEOD-34289 | biostudies-arrayexpress
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