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ProteomicsDynamic adaptation of myocardial proteome during heart failure development after induction of left ventricular pressure overload in mice
We analyzed time dependent global proteomic adaptations during heart failure (HF) progression in a mouse model, suffering from left ventricular pressure overload due to transverse aortic constriction (TAC), to gain deeper insights in the disease development and identify new biomarker candidates. Th...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-16 | PXD007171 | Pride
Heart failure Hspb7 Left ventricle Proteome Right ventricle 
ProteomicsInfluence of the Soluble Guanylate Cyclase Stimulator Riociguat on Myocardial Left Ventricular Proteome and microRNA expression after Experimental Aortic Stenosis in Mice
We analyzed global proteomic adaptations during heart failure (HF) progression in a mouse model, suffering from left ventricular pressure overload due to transverse aortic constriction (TAC) and in response to riociguat (RIO) treatment, to gain deeper insights in beneficial effects due to sGC stimul...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-19 | PXD024156 | Pride
Proteomics Microrna sequencing Cardiac remodeling Tac Heart failure Soluble guanylate cyclase stimulator Riociguat 
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