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TranscriptomicsDiscovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis
Sexual reproduction can promote genetic diversity in eukaryotes, and yet many pathogenic fungi have been labeled as obligate asexual species. It is becoming increasingly clear, however, that cryptic sexual programs may exist in some species, and that efficient mating requires the necessary developme...
ORGANISM(S): Candida tropicalis 
2012-08-28 | E-GEOD-40179 | biostudies-arrayexpress
UnknownSpliceosome-Mediated Pre-mRNA trans-Splicing Can Repair CEP290 mRNA.
Not available
S-EPMC6023944 | biostudies-literature
ProteomicsRibosome quality control activity potentiates vaccinia virus protein synthesis during infection
Ribosomes are highly abundant cellular machines that perform the essential task of translating the genetic code into proteins. Cellular translation activity is finely tuned and proteostasis insults, such as those incurred upon viral infection, activate stress signaling pathways that result in transl...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Vaccinia Virus Wr (ncbitaxon:10254) 
2021-01-05 | MSV000086660 | MassIVE
ProteomicsProteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss
Proteinaceous aggregates containing alpha-synuclein protein called Lewy bodies in the substantia nigra is a hallmark of Parkinson's disease. The molecular mechanisms of Lewy body formation and associated neuronal loss remain largely unknown. To gain insights on proteins and pathways associated with ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD019279 | Pride
Brain Lewy bodies Substantia nigra Lc-ms/ms 
TranscriptomicsMalaria Cell Atlas: Single cell transcriptomics of malaria parasites
Single-cell RNA-sequencing is revolutionising our understanding of seemingly homogeneous cell populations but has not yet been widely applied to single-celled organisms. Transcriptional variation in unicellular malaria parasites from the Plasmodium genus is associated with critical phenotypes includ...
ORGANISM(S): Plasmodium falciparum 3D7 
2017-02-08 | E-ERAD-611 | biostudies-arrayexpress
TranscriptomicsAnalysis of the evolutionary adaptation of an AraC-like global regulatory protein in the murine enteric pathogen Citrobacter rodentium
An experiment to test the equivalence of the Citrobacter rodentium RegA and E.Coli SMS 3-5 homologue 8 Conditions (4 Genotypes by 2 treatments) in duplicate. Reference design without dye swaps.
ORGANISM(S): Citrobacter rodentium 
2015-02-19 | E-GEOD-57689 | biostudies-arrayexpress
ProteomicsLarge Cohort Proteomics Profiling of Human Brain Cortex
LC-MS/MS profiling of mid frontal or inferior temporal cortex from ROS, MAP and KRONOSII cohorts.
ORGANISM(S): Homo sapiens (Human) 
2019-05-13 | PXD006537 | Pride
Alzheimer's Brainome Brain O18-labeling 
ProteomicsABRF PRG 2012: Longitudinal QC in Routine Peptide LC-MS/MS Analyses
Questions concerning data quality and reproducibility of proteomic laboratories spurred the ABRF-PRG group to design a study to systematically assess the reproducibility of proteomic laboratories. Sixty four participants were recruited from the broader mass spectrometry community and were asked to ...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2015-04-28 | MSV000079117 | MassIVE
ProteomicsA SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 170,000 people since the end of 2019, killed over 7,400, and caused worldwide social and economic disruption. SARS-CoV-2 infection has a mortality rate of 3.4% among confirmed case...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-03-24 | MSV000085144 | MassIVE
GenomicsPR
Pharmacogenomic response to Statins samples (Genotypes/Phenotypes)
EGAD00010000282 | EGA
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