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TranscriptomicsHMF3A_with_3Dwt
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. HMF3A cells cease proliferating by 4 days at 39Â...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-688 | biostudies-arrayexpress
TranscriptomicsHMF3A_RNAi
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. The pSUPER-retro vector system (Brummelkamp, 200...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-690 | biostudies-arrayexpress
TranscriptomicsPrim_Fibs
To determine changes in gene expression in primary fibroblasts undergoing replicative senescence, a direct comparison between early passage proliferating cells and senescent cells was performed. Frozen stocks of the primary fibroblasts (HMF3) from which the lines HMF3A and HMF3Dwt were derived (O'Ha...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-687 | biostudies-arrayexpress
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