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TranscriptomicsNLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells
Effect of Monosodium Urate Crystals in wild-type and NLRP3 ko murine dendritic cells
ORGANISM(S): Mus musculus 
2013-07-11 | E-MEXP-3858 | biostudies-arrayexpress
TranscriptomicsSynergism between curdlan and GM-CSF in mouse dendritic cells
A simultaneous engagement of different pathogen recognition receptors provides a tailor made adaptive immunity for an efficient defence against distinct pathogens. For example, cross talk of TLR and c-type lectin signalling effectively shapes distinct gene expression patterns by integrating the sign...
ORGANISM(S): Mus musculus 
2011-10-14 | E-GEOD-32986 | biostudies-arrayexpress
MetabolomicsIntracellular iron overload rewires HSC metabolism by impairing mitochondrial fitness
Iron is an essential element for several cellular processes and recent evidence highlighted its role in regulating the function of hematopoietic stem cells (HSCs). When in excess it reduces quiescence and self-renewal, however, whether and how iron influences HSC metabolism is still unknown. Here, w...
2024-12-04 | MTBLS11778 | MetaboLights
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