Sort   by:  
 Page size 
MetabolomicsMulti-omic profiles of human nonalcoholic fatty liver disease tissue highlight heterogenic phenotypes
Non-alcoholic fatty liver disease (NAFLD) is a consequence of sedentary life style and high fat diets with an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms in, e.g. APOC3, ...
2015-12-07 | MTBLS174 | MetaboLights
GenomicsChIP NS5 Ascl1-ERT2
Here we performed a ChIP-seq experiment on a sample of adherent cultures of mouse neural stem cells (NS5 cell line) under normal growth conditions and upon short term activation (30 minutes) of an inducible version of the proneural factor Mash1/Ascl1 (Ascl1-ERT2). This resulted in the generation of ...
ORGANISM(S): Mus musculus 
2015-02-16 | E-MTAB-2384 | biostudies-arrayexpress
TranscriptomicsSynergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma (Daoy) cells
Aberrant activation of Hedgehog (HH) signaling has been identified as a key etiologic factor of many human malignancies. Signal strength, target gene specificity, and oncogenic activity of HH signaling profoundly depend on interactions with other pathways such as epidermal growth factor receptor-med...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-46045 | biostudies-arrayexpress
ProteomicsHs_GBA1_iPSC_6plex
iPSC-derived neurons from GBA1-associated PD patients
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005155 | PeptideAtlas
TranscriptomicsClassifying distinct grades of human non-alcoholic fatty liver disease employing a systems biology approach
With an estimated prevalence of about 30% in western countries non-alcoholic fatty liver disease (NAFLD) is a major public health issue [PMID: 18956290]. NAFLD is associated with the metabolic syndrome of insulin resistance, obesity, glucose intolerance. Although many studies are pointing to an indu...
ORGANISM(S): Homo sapiens 
2015-11-01 | E-GEOD-46300 | biostudies-arrayexpress
GenomicsChromosome 11 analysis in myeloid malignancies - WES
Blood samples from patients with myeloid malignancies were analyzed using whole exome sequencing (WES). Data set from genotyping by microarray of the same samples has been deposited in ArrayExpress under accession number E-MTAB-1845 (https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-1845/).
ORGANISM(S): Homo sapiens 
2013-11-01 | E-MTAB-1850 | biostudies-arrayexpress
TranscriptomicsChromosome 11 analysis in myeloid malignancies - microarrays
blood samples from patients with myeloid malignancies were analyzed using Affymetrix Genome-Wide Human SNP 6.0 arrays.
ORGANISM(S): Homo sapiens 
2013-11-01 | E-MTAB-1845 | biostudies-arrayexpress
GenomicsCancer Genetic Markers of Susceptibility (CGEMS) Breast Cancer Genome-Wide Association Study (GWAS) - Primary Scan (Stage 1) - Nurses' Health Study

The Cancer Genetic Markers of Susceptibility (CGEMS) breast cancer genome-wide association study (GWAS) included genotyping 528,173 SNPs (Illumina HumanHap550) in 1,145 postmenopausal women of European ancestry with invasive breast cancer and 1,142 controls from the Nurses' Health Study (...

phs000147.v1.p1 | EGA
GenomicsNINDS-Genome-Wide Genotyping in Parkinson's Disease: First Stage Analysis and Public Release of Data

Epidemiological studies have estimated a cumulative prevalence of PD of greater than 1 per thousand. When prevalence is limited to senior populations, this proportion increases nearly 10-fold. The estimated genetic risk ratio for PD is approximately 1.7 (70% increased risk for PD if a sibling...

phs000089.v3.p2 | EGA
GenomicsOCAC OncoArray data
Germline genotype data on 56,479 ovarian cancer cases and controls
EGAD00010001192 | EGA
Sort   by:  
 Page size