Sort   by:  
 Page size 
TranscriptomicsMolecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity
A subfamily of Drosophila homeodomain (HD) transcription factors (TFs) controls the identities of individual muscle founder cells (FCs). However, the molecular mechanisms by which these TFs generate unique FC genetic programs remain unknown. To investigate this problem, we first applied genome-wide ...
ORGANISM(S): Drosophila melanogaster 
2012-01-28 | E-GEOD-35380 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human dormant and angiogenic breast cancer, osteosarcoma, liposarcoma and brain tumor cell lines
The Goal of this study is to explore the transcriptional differences between angiogenic and non-angiogenic tumors generated in Dr. Folkman's Lab, Harvard Medical School.
Referneces:
Almog N, Henke V, Flores L, Hlatky L, Kung AL, Wright RD, Berger R, Hutchinson L, Naumov GN, Bender E, Akslen LA...
ORGANISM(S): Homo sapiens 
2009-02-03 | E-TABM-390 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Vitis vinifera cv. Cabernet-Sauvignon leaves obtained from plants grown in different enviroments and infected with vascular ascomycete fungus Eutypa lata.
Eutypa dieback is a vascular disease that may severely affect vineyards throughout the world. In the present work, microarrays analysis were made in order (i) to improve our knowledge of grapevine (Vitis vinifera cv. Cabernet-Sauvignon) responses to Eutypa lata, the causal agent of Eutypa dieback an...
ORGANISM(S): Vitis vinifera 
2010-03-01 | E-MEXP-2337 | biostudies-arrayexpress
TranscriptomicsSequence specificity incompletely defines the genome-wide occupancy of Myc
The Myc-Max heterodimer is a DNA binding protein that regulates expression of a large number of genes. Genome occupancy of Myc-Max is thought to be driven by E-boxes (CACGTG or variants) to which the heterodimer binds in vitro. By analyzing ChIP-Seq datasets, we demonstrated that the positions occup...
ORGANISM(S): Homo sapiens 
2014-09-22 | E-GEOD-58570 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E.coli cells in the response to Cobalt stress
Analysis used RNA extracted from Escherichia coli exposed or not to cobalt. Experiments were done with E. coli MC4100 cultures exposed to CoCl2 (250 µM) in mid-exponential phase during 30 min. Comparisons were made across multiple arrays, using E. coli MC4100 DNA microarrays spotted with PCR product...
ORGANISM(S): Escherichia coli 
2010-03-01 | E-MEXP-2551 | biostudies-arrayexpress
TranscriptomicsQuantitative modeling of transcription factor binding specificities using DNA shape
Accurate predictions of the DNA binding specificities of transcription factors (TFs) are necessary for understanding gene regulatory mechanisms. Traditionally, predictive models are built based on nucleotide sequence features. Here, we employed three- dimensional DNA shape information obtained on a ...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-59845 | biostudies-arrayexpress
TranscriptomicsStability selection for regression-based models of transcription factor-DNA binding specificity
Motivation: The DNA binding specificity of a transcription factor (TF) is typically represented using a position weight matrix (PWM) model, which implicitly assumes that individual bases in a TF binding site contribute independently to the binding affinity, an assumption that does not always hold. F...
ORGANISM(S): Homo sapiens 
2013-05-17 | E-GEOD-47026 | biostudies-arrayexpress
UnknownTerm infant formula supplemented with milk-derived oligosaccharides shifts the gut microbiota closer to that of human milk-fed infants and improves intestinal immune defense: a randomized controlled trial.
Not available
S-EPMC8755036 | biostudies-literature
UnknownSynthesis of Vinylene-Linked Two-Dimensional Conjugated Polymers via the Horner-Wadsworth-Emmons Reaction.
Not available
S-EPMC7814668 | biostudies-literature
TranscriptomicsAcetyl-CoA metabolism by ACSS2 regulates neuronal histone acetylation and long-term memory [RNA-seq]
Metabolic production of acetyl-CoA has been linked to histone acetylation and gene regulation, however the mechanisms are largely unknown. We show that the metabolic enzyme acetyl-CoA synthetase 2 (ACSS2) is a critical and direct regulator of histone acetylation in neurons and of long-term mammalian...
ORGANISM(S): Mus musculus 
2017-05-01 | E-GEOD-76853 | biostudies-arrayexpress
Sort   by:  
 Page size