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TranscriptomicsHematopoietic Transcriptional Comparison of HSC from B10.BR/JRep and B10.BR/J (drifted) mice
Divergence has occured between the B10.BR-H2k H2-T18a/SgSnJJrep and B10.BR-H2k H2-T18a/SgSnJ (drifted) mouse strains, resulting in altered antigenic recognition and differential bone marrow engraftment capability. The microarray data demonstrate that the transcriptional profile of genes associated w...
ORGANISM(S): Mus musculus 
2009-09-15 | E-GEOD-17471 | biostudies-arrayexpress
ProteomicsDasatinib for the treatment of gastric cancer
Gastric cancer (GC) represents a major health problem, remaining the fifth most common type of cancer and the third leading cause of cancer-related death worldwide with only few targeted therapies available to date. The positive effect of kinase inhibitors on many different types of cancers has prom...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012953 | Pride
Dasatinib Src kinases Gastric cancer Kinobeads 
ProteomicsSingle methyl group positioning opens new chemical space for EPH receptor kinase inhibition
EPHrin receptors (EPH) are transmembrane receptor tyrosine kinases. Their extracellular domains bind specifically to ephrin A/B ligands, and this binding modulates the intracellular kinase activity. EPHs are key players in bidirectional intercellular signalling, controlling cell morphology, adhesion...
ORGANISM(S): Homo sapiens (Human) 
2018-09-05 | PXD009188 | Pride
Eph receptor Selectivity profiling Kinase inhibitor Kinobeads 
TranscriptomicsIL-33 activates tumor stroma to promote intestinal polyposis
Tumor epithelial cells develop within a microenvironment consisting of extracellular matrix, growth factors, and cytokines produced by non-epithelial stromal cells. In response to paracrine signals from tumor epithelia, stromal cells modify the microenvironment to promote tumor growth and metastasis...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-62518 | biostudies-arrayexpress
ProteomicsHuman coronavirus-229E infection alters the structure of host RNA processing complexes
The purpose of this experiment was to evaluate the human host cellular response to wild-type human coronavirus strain 229E (HCoV-229E)(ncbitaxon:11137) infection. Sample data was obtained for mock and infected (MOI 3) immortalized human lung epithelial cells (A549), immortalized human lung fibroblas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-05 | MSV000096303 | MassIVE
ProteomicsHuman coronavirus-229E infection alters the structure of host RNA processing complexes
The purpose of this experiment was to evaluate the human host cellular response to wild-type human coronavirus strain 229E (HCoV-229E)(ncbitaxon:11137) infection. Sample data was obtained for mock and infected (MOI 3) immortalized human lung epithelial cells (A549), immortalized human lung fibroblas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-31 | MSV000096268 | MassIVE
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
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