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TranscriptomicsTranscription profiling of by comparing human breast cancer cell line MDA-MB-468 cyclin E transfected cells with control-transfected cells vs a control
We studied the effect of cyclin E overexpression in the breast cancer cell line MDA-MB-468, by comparing cyclin E transfected cells with control-transfected cells. The cyclin E/control hybridization was performed twice and cDNA from control transfected cells was used as a reference.
ORGANISM(S): Homo sapiens 
2005-05-31 | E-MEXP-339 | biostudies-arrayexpress
TranscriptomicsCo-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition
Although pre-clinical and clinical studies on PARP1 inhibitors, alone and in combination with DNA-damaging agents, show promising results, further ways to improve and broaden the scope of application of this therapeutic approach are warranted. To this end, we have investigated the possibility of imp...
ORGANISM(S): Homo sapiens 
2012-01-19 | E-GEOD-34817 | biostudies-arrayexpress
TranscriptomicsHigh-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer.
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characterize MBC by genomic imbalances and to compare it with female breast cancer (FBC), and further to investigate whether the genomic profiles hold any progn...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-50512 | biostudies-arrayexpress
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