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ProteomicsChemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides
The stress sensors ATF6, IRE1 and PERK monitor deviations from homeostatic conditions in the endoplasmic reticulum (ER), a protein biogenesis compartment of eukaryotic cells. Their activation elicits unfolded protein responses (UPR) to re-establish proteostasis. UPR have been extensively investigate...
ORGANISM(S): Homo sapiens (Human) 
2018-02-16 | PXD008529 | Pride
Proteomics Endoplasmic reticulum stress (er stress) Endoplasmic reticulum (er) Transcriptomics Proteostasis Unfolded protein response (upr) 
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