Sort   by:  
 Page size 
TranscriptomicsQuantification of Normal Cell Fraction and Copy Number Neutral LOH in Clinical Lung Cancer Samples Using SNP Array Data
Technologies based on DNA microarrays have the potential to provide detailed information on genomic aberrations in tumor cells. In practice a major obstacle for quantitative detection of aberrations is the heterogeneity of clinical tumor tissue. Tumor tissue consists of a mixture of tumor cells and ...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-16092 | biostudies-arrayexpress
TranscriptomicsGene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (copy number data)
Hypothesis: Non-small cell lung cancer (NSCLC) is characterized by a multitude of genetic aberrations with unknown clinical impact. In this study, we aimed to identify gene copy number changes that correlate with clinical outcome in NSCLC. To maximize the chance to identify clinically relevant event...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-28572 | biostudies-arrayexpress
TranscriptomicsCD99 is a novel prognostic stromal marker in non-small cell lung cancer
The delicate interaction between cancer cells and the surrounding stroma plays an essential role in all stages of tumourigenesis. Despite the significance of this interplay, alterations in protein composition underlying tumour-stroma interactions are largely unknown. The aim of this study was to ide...
ORGANISM(S): Homo sapiens 
2012-06-05 | E-GEOD-33363 | biostudies-arrayexpress
TranscriptomicsGene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non-Small Cell Lung Cancer (expression data)
Hypothesis: Non-small cell lung cancer (NSCLC) is characterized by a multitude of genetic aberrations with unknown clinical impact. In this study, we aimed to identify gene copy number changes that correlate with clinical outcome in NSCLC. To maximize the chance to identify clinically relevant event...
ORGANISM(S): Homo sapiens 
2011-10-27 | E-GEOD-28571 | biostudies-arrayexpress
TranscriptomicsBiomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis and tissue microarray validation
Background: Global gene expression profiling has been widely used in lung cancer research to identify clinically relevant molecular subtypes as well as to predict prognosis and therapy response. So far, the value of these multi-gene signatures in clinical practice is unclear and the biological impor...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-37745 | biostudies-arrayexpress
Sort   by:  
 Page size