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TranscriptomicsRole of Ado1p in the transcriptional response associated with AICAr supplementation
We investigated the role of Ado1p associated with AICAr supplementation on the global transcriptome of Y3188. The Y3188 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29020 | biostudies-arrayexpress
TranscriptomicsEffect of 5-amino-4-imidazolecarboxamide ribotide (AICAr) supplementation on global transcription
We investigated the effects of AICAr supplementation on the global transcriptome of Y2950. The Y2950 strain was grown with or without AICAr. For each comparison, we made 2 biological replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29019 | biostudies-arrayexpress
TranscriptomicsEffect of AICAr and SAICAr accumulation on global transcription in the ade3 mutant
We investigated the effects of AICAr and SAICAr accumulation on the global transcriptome of yeast, comparing the ade3 mutant to the WT strain. The ade3 mutant strain (Y4143) was compared to the WT strain (Y2946). For each comparison, we made 2 technical replicates, swapping dyes.
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-31 | E-GEOD-29021 | biostudies-arrayexpress
GenomicsBromodomain-dependent stage-specific male genome programming by Brdt
This SuperSeries is composed of the following subset Series: GSE39908: Bromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq] GSE39909: Bromodomain-dependent stage-specific male genome programming by Brdt [Illumina BeadArray] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39910 | biostudies-arrayexpress
OtherForty-Four Novel Protein-Coding Loci Discovered Using a Proteomics Informed by Transcriptomics (PIT) Approach in Rat Male Germ Cells.
Data from ProteomeXchange, PXD ID: PXD000872. File: SPC_exc02_compil.msf.mgf. Published as part of Biol Reprod. 2014 Sep 10 . From the Abstract: {{i}} Spermatogenesis is a complex process, dependent upon the successive activation and/or repression of thousands of gene products, and ends with the pr...
ORGANISM(S): Mus_musculus_viruses,rattus_norvegicus_papillomavirus_1_ees_2009_uid40233,rat_coronavirus_parker_uid39313, Rat 
GPM32320003462 | GPMDB
Resource Reanalysis 
TranscriptomicsBromodomain-dependent stage-specific male genome programming by Brdt [Illumina BeadArray]
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39909 | biostudies-arrayexpress
GenomicsBromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq]
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39908 | biostudies-arrayexpress
TranscriptomicsDose-dependent immunomodulation of human dendritic cells by the probiotic Lactobacillus rhamnosus Lcr35
Gene expression changes in human dendritic cells after contact with either 10e4 or 10e7 CFU of Lactobacillus rhamnosus Lcr35 Bacterial cells were incubated for 3 hours with dendritic cells. Total RNA was extracted, quantified, and labeled with Cy3 or Cy5 (control, dendritic cells without bacteria). ...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-25699 | biostudies-arrayexpress
TranscriptomicsHypermethylated capped selenoprotein mRNAs in mammals
Mammalian mRNAs are generated by complex and coordinated biogenesis pathways and acquire 5'-end m7G caps that play fundamental roles in processing and translation. Here we show that several selenoprotein mRNAs are not recognized efficiently by translation initiation factor eIF4E because they bear a ...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-57625 | biostudies-arrayexpress
TranscriptomicsTye7 regulates yeast Ty1 retrotransposon sense and antisense transcription in response to adenylic nucleotides stress
We investigated the effects of adenine starvation on the global yeast transcriptome. In this work, global transcription analyses were combined with measurements of intracellular nucleotides pools by HPLC. The bas1delta strain grown with or without adenine was compared to the WT strain grown with or ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-10 | E-GEOD-28579 | biostudies-arrayexpress
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