Sort   by:  
 Page size 
Transcriptomicsp27Kip1 regulates cell cycle progression by modulating the expression of p21Cip1
In addition to its classical role as a CDK inhibitor, p27 also acts as a transcriptional regulator. We found that at early passages, embryonic fibroblasts from p27-/- mouse show reduced expression of genes involved in DNA replication and progress slowly through the cell cycle. These cells have high ...
ORGANISM(S): Mus musculus 
2016-06-09 | E-MTAB-2790 | biostudies-arrayexpress
UnknownPolymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation.
Not available
S-EPMC4687226 | biostudies-literature
Transcriptomicsp27 binds to promoters of multiple genes leading to their repression
The role of the cyclin-cdk inhibitor p27 in tumorigenesis is still a controversial matter. We demonstrate here that p27 negatively regulates transcription of a number of genes (p27-target genes) involved in key cellular functions as RNA processing, translation, respiration and cell proliferation. Cr...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-20068 | biostudies-arrayexpress
TranscriptomicsExpression data from p27delta51 MEFs cells in quiescence
Low levels of the cell cycle regulator p27Kip1 are associated with a worse outcome in many tumor types. We report here a new regulatory role of p27Kip1 as a transcriptional regulator. In association with transcriptional repressors such as p130, E2F4 and HDACs, p27 binds to promoters of multiple gene...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-20064 | biostudies-arrayexpress
TranscriptomicsExpression data from p27WT, p27CK and KO MEFs cells in quiescence
Low levels of the cell cycle regulator p27Kip1 are associated with a worse outcome in many tumor types. We report here a new regulatory role of p27Kip1 as a transcriptional regulator. In association with transcriptional factors such as ETS and E2F4 and co-repressors like p130, HDACs and mSin3A, p27 ...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-27672 | biostudies-arrayexpress
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
UnknownElective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.
Not available
S-EPMC9621702 | biostudies-literature
Sort   by:  
 Page size